Results 111 to 120 of about 17,207,506 (302)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

icenReg: Regression Models for Interval Censored Data in R

open access: yesJournal of Statistical Software, 2017
The non-parametric maximum likelihood estimator and semi-parametric regression models are fundamental estimators for interval censored data, along with standard fullyparametric regression models.
Clifford Anderson-Bergman
doaj   +1 more source

Methods of competing risks flexible parametric modeling for estimation of the risk of the first disease among HIV infected men

open access: yesBMC Medical Research Methodology, 2020
Background Patients infected with the Human Immunodeficiency Virus (HIV) are susceptible to many diseases. In these patients, the occurrence of one disease alters the chance of contracting another.
Sahar Nouri   +5 more
doaj   +1 more source

ESTIMATING NON-PARAMETRIC AND PARAMETRIC TRANSFORMATION FUNCTIONS FROM SURVEY DATA: AN APPLICATION OF MINIMUM CROSS-ENTROPY [PDF]

open access: yes
A model of a (convex) technology of representative and non-representative firms in a heterogeneous sector is presented in non-parametric and parametric versions. The heterogeneity is specified with error terms.
Hoveid, Oyvind
core  

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Non-parametric correlation structures and their respective embeddings in predictive analysis

open access: yesDiscover Applied Sciences
In data analysis, there is a natural connection between correlation and visual analysis. Correlation analysis enables the identification of relationships between attribute pairs in multidimensional datasets, while visual data analysis focuses on ...
Adam Dudáš
doaj   +1 more source

GDP nowcasting with ragged-edge data : A semi-parametric modelling [PDF]

open access: yes
This papier formalizes the process of forecasting unbalanced monthly data sets in order to obtain robust nowcasts and forecasts of quarterly GDP growth rate through a semi-parametric modelling.
Patrick Rakotomarolahy   +2 more
core  

Parametric Interpretation of Non-Parametric Regression Models [PDF]

open access: yes, 2014
The advantage of the parametric regression models is the possibility of interpretation of the parameters of the regression model, i.e. to determine the direction and strength of the influence of predictors on the dependent variable.
Stelmach, Jacek
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Non-parametric state space models (монография) [PDF]

open access: yes, 2013
Аннот. на кн. : Добровидов А. В., Кошкин Г. М., Васильев В. А. Non-Parametric State Space Models : книга на англ. яз. Heber, USA : Kendrick Press, 2012.
Добровидов, Александр Викторович   +2 more
core   +1 more source

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