Results 81 to 90 of about 16,266,310 (309)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Semi-parametric models for response times and response accuracy in computerized testing [PDF]

open access: yes, 2012
In computer-administered tests, response times can be recorded conjointly with the corresponding responses. This broadens the scope of potential modeling approaches because response times can be analyzed in addition to analyzing the responses themselves.
Wang, Chun
core  

Non-parametric Latent Modeling and Network Clustering [PDF]

open access: yes, 2020
The paper exposes a non-parametric approach to latent and co-latent modeling of bivariate data, based upon alternating minimization of the Kullback-Leibler divergence (EM algorithm) for complete log-linear models. For categorical data, the iterative algorithm generates a soft clustering of both rows and columns of the contingency table.
openaire   +2 more sources

A SPLINE MODEL FOR ELECTRICITY DEMAND FORESCASTING UN MODELO SPLINE PARA EL PRONÓSTICO DE LA DEMANDA DE ENERGÍA ELÉCTRICA

open access: yesRevista Colombiana de Estadística, 2007
Our goal is to model, with forecasting aims, the daily electricity demand in a southeast colombian region through a non-parametric regression model implementation. We consider some “calendar variables” such as time of the day, day of the week, month, and
Barrientos Andrés Felipe   +2 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Non-parametric estimation of forecast distributions in non-linear, non-gaussian state space models

open access: yes, 2017
Non-Gaussian time series variables are prevalent in the economic and finance spheres, with state space models often employed to analyze such variables and, ultimately, to produce forecasts.
Ng, Jason Wei Jian (3718801)
core   +1 more source

Correlated Non-Parametric Latent Feature Models

open access: yesCoRR, 2012
Appears in Proceedings of the Twenty-Fifth Conference on Uncertainty in Artificial Intelligence (UAI2009)
Finale Doshi-Velez, Zoubin Ghahramani
openaire   +3 more sources

New Agricultural Tractor Manufacturer’s Suggested Retail Price (MSRP) Model in Europe

open access: yesAgriculture
Research investigating models for assessing new tractor pricing is notably scarce, despite its fundamental importance in conducting comprehensive cost analyses.
Ivan Herranz-Matey, Luis Ruiz-Garcia
doaj   +1 more source

A non-parametric hidden Markov model for climate state identification [PDF]

open access: yesHydrology and Earth System Sciences, 2003
Hidden Markov models (HMMs) can allow for the varying wet and dry cycles in the climate without the need to simulate supplementary climate variables. The fitting of a parametric HMM relies upon assumptions for the state conditional distributions.
M. F. Lambert   +3 more
doaj  

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