Results 81 to 90 of about 16,851,240 (304)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A Non-parametric Spectral Model for Graph Classification
Proceedings of the International Conference on Pattern Recognition Applications and Methods, 2015 Graph-based representations have been used with considerable success in computer vision in the abstraction and recognition of object shape and scene structure. Despite this, the methodology available for learning structural representations from sets of training examples is relatively limited.
Andrea Gasparetto +2 more
openaire +2 more sources
Fault Localization with Non-parametric Program Behavior Model [PDF]
2008 The Eighth International Conference on Quality Software, 2008 Fault localization is a major activity in software debugging. Many existing statistical fault localization techniques compare feature spectra of successful and failed runs. Some approaches, such as SOBER, test the similarity of the feature spectra through parametric self-proposed hypothesis testing models.
Peifeng Hu +3 more
openaire +3 more sources
Beta-Stacy survival regression models [PDF]
, 2007 This paper introduces a class of survival models for discrete time-to-event data with random right censoring. Flexible distributions for the survival times are constructed by modelling the random survival functions as discrete-time beta-Stacy processes (
Muliere, Pietro, Rigat, Fabio
core
Estimating individual tree growth with the k-nearest neighbour and k-Most Similar Neighbour methods
Silva Fennica, 2001 The purpose of this study was to examine the use of non-parametric methods in estimating tree level growth models. In non-parametric methods the growth of a tree is predicted as a weighted average of the values of neighbouring observations.
Sironen, Susanna +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Un modelo spline para el pronóstico de la demanda de energía eléctrica
Revista Colombiana de Estadística, 2007 El propósito de este trabajo es modelar, con fines de pronóstico, la demanda diaria de energía eléctrica en una región del suroccidente colombiano, mediante la implementación de modelos de regresión no paramétrica teniendo en cuenta factores de ...
ANDRÉS FELIPE BARRIENTOS +2 more
doaj
Geosystems and GeoenvironmentClimate change is considered a long-term change in precipitation, temperature and other meteorological variables. The pattern of meteorological variables is changing due to anthropogenic activities globally. Climate change has posed threat to natural and
Md Masroor, Haroon Sajjad
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source