Results 61 to 70 of about 282,414 (265)
Big Data and Cognitive Computing, 2020 YouTube is a boon, and through it people can educate, entertain, and express themselves about various topics. YouTube India currently has millions of active users.
Sonali Rajesh Shah +3 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Bayesian Non-Parametric Inference for Multivariate Peaks-over-Threshold Models
EntropyWe consider a constructive definition of the multivariate Pareto that factorizes the random vector into a radial component and an independent angular component. The former follows a univariate Pareto distribution, and the latter is defined on the surface
Peter Trubey, Bruno Sansó
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Estimating individual tree growth with the k-nearest neighbour and k-Most Similar Neighbour methods
Silva Fennica, 2001 The purpose of this study was to examine the use of non-parametric methods in estimating tree level growth models. In non-parametric methods the growth of a tree is predicted as a weighted average of the values of neighbouring observations.
Sironen, Susanna +3 more
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PLoS ONE, 2023 BackgroundMany studies analyze sexual and reproductive event data using descriptive life tables. Survival analysis has better power to estimate factors associated with age at first sex (AFS), but proportional hazards models may not be right model to use.
Jacqueline Materu +5 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
DWT based non-parametric texture modeling [PDF]
Proceedings 2001 International Conference on Image Processing (Cat. No.01CH37205), 2002 We propose a non-parametric texture modeling and synthesis technique based on the integer version of the discrete wavelet transform (DWT). The successive levels of the DWT pyramid of the input texture are progressively sampled starting from the signal approximation to generate the analogous wavelet pyramid for the synthetic texture.
openaire +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Un modelo spline para el pronóstico de la demanda de energía eléctrica
Revista Colombiana de Estadística, 2007 El propósito de este trabajo es modelar, con fines de pronóstico, la demanda diaria de energía eléctrica en una región del suroccidente colombiano, mediante la implementación de modelos de regresión no paramétrica teniendo en cuenta factores de ...
ANDRÉS FELIPE BARRIENTOS +2 more
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