Results 141 to 150 of about 921,406 (312)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Quantile Non‑parametric Additive Models
Acta Universitatis Lodziensis. Folia Oeconomica, 2019 Quantile regression allows us to assess different possible impacts of covariates on different quantiles of a response variable. Additive models for quantile functions provide an attractive framework for non‑parametric regression applications focused on functions of the response instead of its central tendency. Total variation smoothing penalties can be
openaire +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Bayesian Semi- and Non-parametric Models for Longitudinal Data with Multiple Membership Effects in R. [PDF]
J Stat Softw, 2014 Savitsky TD, Paddock SM.
europepmc +1 more source
ROBUSTNESS OF NON-PARAMETRIC MEASUREMENT OF EFFICIENCY AND RISK AVERSION
This paper examines the performance of a risk-adjusted non-parametric approach to measuring efficiency and risk aversion. Prior work is extended to the case where agent behavior is motivated by expected utility maximization. Results indicate the approach
Settlage, Daniel M., Preckel, Paul V.
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Mass models of galaxy clusters from a non-parametric weak-lensing reconstruction
The Open Journal of AstrophysicsWe study the CLASH sample of galaxy clusters using a new deprojection method for weak gravitational lensing observations. This method is non-parametric, allowing us to infer mass profiles, or equivalently circular velocities, without having to assume a ...
Tobias Mistele +4 more
doaj +1 more source
Software Reliability Prediction Based on Recurrent Neural Network and Ensemble Method
ComputersSoftware reliability is a crucial factor in determining software quality quantitatively. It is also used to estimate the software testing duration. In software reliability testing, traditional parametric software reliability growth models (SRGMs) are ...
Wafa Alshehri +2 more
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Classification rates: non‐parametric verses parametric models using binary data
, 2015 Estimations of the conditional mean and the marginal effects for particular small changes in the covariates have been of interest in financial, economics and even educational sectors.
Otieno, RO, Gichuhi, AW, Adem, AO
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source