Results 101 to 110 of about 805,503 (353)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Active stabilization for ultralong acquisitions in an attosecond pump–probe beamline

open access: yesAPL Photonics
Attosecond time-resolution experiments using noncollinear interferometers require precise and active control of the optical delay to prevent instabilities—including both slow drifts and rapid vibrations—that can obscure the time evolution of the physical
Tamás Csizmadia   +7 more
doaj   +1 more source

The Non-profit Sector in Kenya: What We Know and What We Don't Know [PDF]

open access: yes, 2007
The primary aim of this publication is to set the stage for deepening our knowledge of the non-profit sector in Kenya.
Karuti Kanyinga, Winnie Mitullah
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Histomorphologic Assessment of the Internal Thoracic Artery in Patients Undergoing Coronary Artery Bypass Grafting: Impact of Smoking

open access: yesУкраїнський журнал серцево-судинної хірургії
Aim. To identify the age- and smoking-related histopathological changes in the internal thoracic artery (ITA) in patients with coronary artery disease (CAD). Materials and Methods. A histopathological study was performed on cross-sections of discarded
Tetiana M. Solomenchuk   +2 more
doaj   +1 more source

Funding and Taxation of Greek Non Profit Organizations and Enterprises [PDF]

open access: yes
Surely, the economic aspect of non profit organizations is very interesting. The aim of the enterprises of this type is not to maximize their profits but to minimize their operational expenses, in order to survive.
Chrysanthi Balomenou   +2 more
core  

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