Results 151 to 160 of about 11,026,292 (311)

Next generation of non-profit leaders: what skills and experiences do future non-profit leaders need to be successful?

open access: yes
This research investigates the essential skills and experiences required for the next generation of non-profit leaders in India. Through expert interviews, key themes emerged including adaptability, innovation, data-driven decision making, collaboration,
Nghiem, Xuan-Hoa   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Credit risk and Basel II: Are non-profit firms financially different? [PDF]

open access: yes
We estimate a model of credit risk for portfolios of Small and Medium-sized enterprises, conditional on being a non-profit or for-profit firms. The estimation is based on a unique dataset on Italian firms provided by a large commercial bank. We show that
Massimiliano Marzo   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Development of road transport emission standards

open access: yesProduction Engineering Archives, 2015
Emissions from road vehicles are playing an important role in air quality which has a significant impact on human health. Pollut-ant emissions have to be precisely determined to ensure that air quality plans are designed and realized properly.
Eszter Horvath, Adam Torok
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Dall'istituto azienda non profit all'impresa sociale

open access: yes, 2013
L’obiettivo di questo saggio è definire l’oggetto di studio dell'intero libro: attraverso l’analisi della letteratura italiana e straniera si cercherà di fornire una definizione di azienda non profit e di impresa sociale, tenendo in dovuta ...
BANDINI, FEDERICA
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Value Co-creation in Non-profit Accommodation Platforms. [PDF]

open access: yesFront Psychol, 2021
Medina-Hernandez VC   +2 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy