Analysis of Differences in Attitudes Between Managers and Non-Managing Employees [PDF]
The basic task of managers is to establish and maintain the conditions required for joint activities of individuals aimed at efficient achievement of goals set by the organization they work for.
Gordana Dukic
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Managing sustainable non-profit network organizations [PDF]
, 2008 We draw upon a case study conducted within a non-profit network organization to propose five dualities which are central to understanding effective management of non-profit networks.
Baker, E +5 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The Effect of Supply Chain Integration, Management Commitment, and Sustainable Supply Chain Practices on Non-profit Organizations Performance Using SEM-FsQCA: Empirical Evidence in Afghanistan [PDF]
This study investigates the impact of supply chain integration, management commitment, and sustainable supply chain practices on non-profit organization performance. The research, centered on non-profit organizations in Afghanistan, employs Structural
Shahzad, Sayed Khalid
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Analisis Pengaruh Reputasi Organisasi dan Kinerja Keuangan terhadap Kontribusi Organisasi Nirlaba [PDF]
, 2017 This study aims to examine the effect of reputation and financial performance to nonprofit contributions. Reputation as an independent variable measured by the age and the size of the non-profit organization, while financial performance is proxy through ...
Achmad, T. (Tarmizi) +1 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Hands-On educational model in Nigeria increases interest in STEM careers
Annals of Global Health, 2016 T. Ajayi +8 more
doaj +1 more source
Once & For All: Placing a Highly Qualified Teacher in Every Philadelphia Classroom [PDF]
, 2003 Quality teaching matters - particularly for low-income, inner-city students who perform below grade level. But these students are often taught by the least-qualified and least-experienced teachers. Philadelphia schools will not be able to improve student
Elizabeth Useem +3 more
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source