Results 101 to 110 of about 270,616 (305)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The redistributive role of non-profit organizations

open access: yes
By starting from the consideration that non-profit organizations cover a significant re-distributive function beside that of governmental agencies, the paper questions why government prefers to finance via transfers private entities likewise lucrative ...
Cerulli, Giovanni
core  

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Managerial discretion, incentives and governance rules for non-profit organizations

open access: yes
This paper analyzes the effects of managerial discretion and some possible solutions in non-profit sector. It is shown how the traditional incentives’ mechanisms are modified in a non-profit setting.
Antonelli, Maria Alessandra
core  

«Relevant correlation» and real typology of dependences on the example of indicators of popular psychological tests

open access: yesВестник Мининского университета
Introduction. The analysis of statistical relation between the characteristics under study is most likely the main type of analytical tasks encountered in almost any psychological study.
M. M. Basimov
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Marketing for non-profit organization

open access: yes, 2013
Bakalářská práce se zabývá marketingem neziskové organizace. Nejprve se věnuje základním teoretickým poznatkům v oblasti marketingu a neziskových organizací. Poté následuje charakteristika vybrané neziskové organizace-Projekt Můj nový život.
Kabíčková, Edita
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Motivation- comparison of profit organization and non-profit organization

open access: yes, 2015
The aim of the Bachelor's thesis is to compare motivation factors in profit sector and non-profit sector. The theoretical part is devoted to the basic concepts of motivation, stimulation, theories of work motivation and work behaviour. In the theoretical
Koňařová, Zuzana
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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