Results 121 to 130 of about 21,300,426 (351)

Comments on Fouchier's Calculation of Risk and Elapsed Time for Escape of a Laboratory-Acquired Infection from His Laboratory

mBio, 2015
Lynn C. Klotz
doaj   +1 more source

Sustainable nuclear non-proliferation. Case-study: Iran

Intergenerational Justice Review
Sustainable nuclear non-proliferation is only possible in a world without nuclear weapons. As long as there are nuclear weapons, the odds are that nuclear proliferation will happen, despite the existence of a comprehensive nuclear non-proliferation ...
Tom Sauer
doaj   +1 more source

Generation of somatic cell hybrids for the production of biologically active factors that stimulate proliferation of other cells

, 2007
Objective: Some normal somatic cells in culture divide a limited number of times before entering a non-dividing state called replicative senescence and fusion of normal cells with immortal cells claimed to produce hybrid cells of limited proliferation ...
Panduri, V, Islam, Khaleda,, Islam, Quamrul,   +2 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Argentina-Brazil nuclear non-proliferation initiatives

, 1994
SIGLEGBUnited ...
Programme for Promoting Nuclear Non-Proliferation, Southampton (United Kingdom), Redick, J.R   +1 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Germany, Europe and nuclear non-proliferation

, 1991
SIGLEGBUnited ...
Programme for Promoting Nuclear Non-Proliferation, Southampton (United Kingdom), Koetter, W., Mueller, H   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Russia´s Non-Proliferation Policy and the Challenges of Rogue Proliferation

Revista UNISCI, 2012
Este artículo analiza el papel de Rusia en los esfuerzos globales de no-proliferación, ofreciendo una visión global sobre la no proliferación rusa, desarme y políticas de control de armamentos.
Natividad Fernández
doaj  

Aid Proliferation and Economic Growth: A Cross-Country Analysis [PDF]

In this paper, we examine whether aid proliferation hinders aid effectiveness in promoting economic growth. We employ a wide variety of specifications of the standard aid-growth regression using Roodman's (2007a) dataset. Specifically, we include a donor-
KIMURA Hidemi, MORI Yuko, SAWADA Yasuyuki   +2 more
core