Results 101 to 110 of about 21,652 (222)

Increase in soluble RAGE following intensive insulin therapy is associated with β‐cell functional improvement and glycemic remission in newly diagnosed type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Short‐term intensive insulin therapy (SIIT) markedly increased circulating sRAGE levels in newly diagnosed type 2 diabetes. The magnitude of sRAGE elevation was associated with improved β‐cell function and a higher likelihood of short‐term glycemic remission.
Qimou Chen, Fang Wei, Jiajing Ma, Xuhui Li, Boyuan Liu, Yanbing Li   +5 more
wiley   +1 more source

Targeting pericyte retention in Diabetic Retinopathy: a review

Annals of Medicine
Diabetic retinopathy is a common yet severe complication of diabetes mellitus and is the leading cause of blindness in middle-aged adults. After years of poorly managed hyperglycemia, complications begin as non-proliferative diabetic retinopathy but can ...
Forrest Bohler, Lily Bohler, Varna Taranikanti   +2 more
doaj   +1 more source

Intraretinal Microvascular Abnormalities and Venous Beading Have Different Genetic Profiles in Caucasian Patients with Non-Proliferative Diabetic Retinopathy. [PDF]

Vision (Basel), 2023
Pearce E, Sivaprasad S, Broadgate S, Kiire C, Downes SM, Halford S, Chong V.   +6 more
europepmc   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

Causal association between cystatin C and diabetic retinopathy: A two‐sample Mendelian randomization study

Journal of Diabetes Investigation
Objective To explore the causal relationship between cystatin C levels and different stages of diabetic retinopathy through Mendelian randomization (MR).
Yimeng Ruan, Ping Zhang, Xiangzhe Li, Xinru Jia, Dongwei Yao   +4 more
doaj   +1 more source

Pseudophakic Cystoid Macular Oedema (PCME) Prevention in Patients with Non-Proliferative Diabetic Retinopathy (NPDR)-Randomized Controlled Trial. [PDF]

Medicina (Kaunas), 2022
Jukić A, Kasalica Žužul R, Pavan J, Lovrić M, Kozmar A, Plavec D, Kuzman T, Kalauz M, Jukić T.   +8 more
europepmc   +1 more source

Sustained moderate visual loss as a predictive end point for visual loss in non-proliferative diabetic retinopathy [PDF]

, 2008
Aniz Girach, Lloyd Paul Aiello, R. C. Milton, Matthew D. Davis, Ronald P. Danis, Xu–Ting Zhi, Matthew J. Sheetz, Louis Vignati, L Vignati   +8 more
openalex   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

Azelaic acid and guanosine in tears improve discrimination of proliferative from non-proliferative diabetic retinopathy in type-2 diabetes patients: A tear metabolomics study. [PDF]

Heliyon, 2023
Wen X, Ng TK, Liu Q, Wu Z, Zhang G, Zhang M.   +5 more
europepmc   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source