Diabetic retinopathy for the non-ophthalmologist
, 2022 Diabetic retinopathy is a microangiopathy resulting from the chronic effects of diabetes mellitus. Healthcare professionals often work in isolation to deliver highly specialised care efficiently and effectively for people living with diabetes.
Amoaku, Winfried MK +3 more
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Development of a cost-effectiveness model for optimisation of the screening interval in diabetic retinopathy screening [PDF]
, 2015 BACKGROUND: The English NHS Diabetic Eye Screening Programme was established in 2003. Eligible people are invited annually for digital retinal photography screening.
Ramon Luengo-Fernandez +18 more
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Electroretinogram Analysis In Patients With Non-Proliferative Diabetic Retinopathy
, 2021 Abstract Purpose: Non-proliferative diabetic retinopathy (NPDR) is the earliest stage of diabetic eye disease. Microscopic changes occur in the blood vessels of the eye in NPDR. The changes typically do not produce symptoms and are not visible to the naked eye.
Zahra Maleki +2 more
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The unmet need for better risk stratification of non‐proliferative diabetic retinopathy [PDF]
Diabetic Medicine, 2018 AbstractDiabetic retinopathy is a common microvascular complication of diabetes and remains one of the leading causes of preventable blindness in working‐age people. Non‐proliferative diabetic retinopathy is the earliest stage of diabetic retinopathy and is typically asymptomatic.
S. Sivaprasad, E. Pearce
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Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema [PDF]
, 2010 Background: Our purpose was to compare the effect of triamcinolone and bevacizumab (Avastin) on the retinal thickness and functional outcome in patients with diabetic macular edema. Methods and Materials: A collective of 32 patients, who had been treated
Haritoglou, Christos +6 more
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Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Advanced Healthcare Materials, EarlyView.Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Robust detection of microaneurysms for sight threatening retinopathy screening [PDF]
, 2008 Diabetic retinopathy is one of the major causes of blindness. However diabetic retinopathy does not usually cause a loss of sight until it has reached an advanced stage.
Bhalerao, Abhir +7 more
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Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Advanced Science, EarlyView.In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source
Prevalence of visual impairment and severity of diabetic retinopathy in various ethnic groups in the UK [PDF]
, 2011 Diabetic Retinopathy (DR) is a leading cause of visual impairment (VI) in the working population. Minor ethnic groups are at increased risk of diabetes.
Gupta, Bhaskar
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