Results 41 to 50 of about 29,450 (234)

Oxidants, antioxidants and mitochondrial function in non-proliferative diabetic retinopathy.

Journal of diabetes, 2014
Diabetic retinopathy (DR) is a preventable cause of visual disability. The aims of the present study were to investigate levels and behavior oxidative stress markers and mitochondrial function in non-proliferative DR (NPDR) and to establish the correlation between the severity of NPDR and markers of oxidative stress and mitochondrial function.In a ...
Rodríguez-Carrizalez, Adolfo Daniel, Castellanos-González, José Alberto, Martínez-Romero, Esaú César, Miller-Arrevillaga, Guillermo, Villa-Hernández, David, Hernández-Godínez, Pedro Pablo, Ortiz, Genaro Gabriel, Pacheco-Moisés, Fermín Paul, Cardona-Muñoz, Ernesto Germán, Miranda-Díaz, Alejandra Guillermina   +9 more
openaire   +2 more sources

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Retro-mode imaging of fibrovascular membrane in proliferative diabetic retinopathy after intravitreal bevacizumab injection [PDF]

, 2011
Kiyoshi Suzuma, Eiko Tsuiki, Makiko Matsumoto, Azusa Fujikawa, Takashi KitaokaDepartment of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, JapanAbstract: The F10 is a new commercially available ...
Tsuiki, Eiko, Kitaoka T, Kiyoshi Suzuma, null Matsumoto, Fujikawa A, Tsuiki E, Suzuma, Kiyoshi, Fujikawa, Azusa, null Kitaoka, null Fujikawa, Suzuma K, null Tsuiki, Matsumoto M, Matsumoto, Makiko, Kitaoka, Takashi   +14 more
core   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Rovetto, Michele Rinaldi, Maurizio Guida, Ciro Costagliola   +6 more
wiley   +1 more source

Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy

Medicine, 2019
Abstract This study retrospectively evaluated the effect of lutein supplement (LS) on patients with non-proliferative diabetic retinopathy (NPDR). A total of 72 patients with NPDR were included in this study. All patients received Zeaxanthin during the study period. In addition, 36 patients also received LS and were
Ren, Yong-bo, Qi, Yan-xiu, Su, Xing-jie, Luan, He-qun, Sun, Qi   +4 more
openaire   +2 more sources

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Current and new concepts in the diagnosis and management of diabetic macular oedema [PDF]

, 2013
Diabetic macular oedema, which can cause rapid visual deterioration, may not have early warning signs at times. Assessment of diabetic retinal complications is made chiefly by clinical examination combined with optical coherence tomography (OCT) and ...
Jyothi, Sreedhar
core  

Different Mechanisms Causing Macular Hole Development in Proliferative Diabetic Retinopathy

, 2012
Macular hole can be defined as the retinal defect involving the foveal region. Anatomically, it may be lamellar or full thickness. Other than senile idiopathic cases, trauma, high myopia and retinal detachment may be among the etiological factors ...
Sinan Tatlıpınar
core   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng, Ling‐Li Chang, Hung‐Chen Wang, Wei‐Chun Hung, Chia‐Hua Hsieh, Yi‐Hsuan Wang, Kuang‐I Cheng   +6 more
wiley   +1 more source

Glycemic Control, Animal Protein Intake, and the Risk of Diabetic Retinopathy Progression Among Patients With Type 2 Diabetes

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Effective glycemic control and food consumption play crucial roles in modulating diabetic retinopathy (DR) progression. This observational longitudinal study explored the hemoglobin A1c (HbA1c) and dietary patterns and their associations with the risk and progression of DR among 369 individuals with type 2 diabetes.
Yu‐Ju Wu, Chih‐Cheng Hsu, Chih‐Yiu Tsai, Shang‐Jyh Hwang, Kun‐Der Lin, Pi‐Chen Lin, Ya‐Fang Huang, Chiao‐I Chang, Meng‐Chuan Huang   +8 more
wiley   +1 more source