Results 41 to 50 of about 10,365,683 (253)

Alcohol: another risk factor for diabetic retinopathy? [PDF]

, 1984
In a five year prospective study clinical features associated with the development and progress of retinopathy were sought in 296 randomly selected diabetic men aged 20-59.
McCulloch, D K, Young, R.J, Clarke, B. F., Prescott, Robin J   +3 more
core  

Association of serum vitamin D and parathormone levels in patients of type 2 diabetes mellitus with diabetic retinopathy

Bangabandhu Sheikh Mujib Medical University Journal, 2017
The present study was aimed to evaluate the association of serum 25-hydroxy vitamin D and parathormone in 46 patients of type 2 diabetes mellitus with diabetic retinopathy [non-proliferative, (n=27); proliferative (n=19)].
Mohammad Shiblee Zaman, Md. Matiur Rahman, Subrata Kumar Biswas, Md. Mozammel Hoque, Khondakar Alwan Nahid   +4 more
doaj   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

Advanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu, Jingfan Wang, Pengfei Ge, Qinyuan Gu, Hongying Li, Yuanyuan Fan, Haiyue Xie, Yangyang Lu, Yifan Lin, Xinjing Wu, Chengkun Wang, Ping Xie, Zizhong Hu   +12 more
wiley   +1 more source

Automatic non-proliferative diabetic retinopathy screening system based on color fundus image

BioMedical Engineering OnLine, 2017
Background Non-proliferative diabetic retinopathy is the early stage of diabetic retinopathy. Automatic detection of non-proliferative diabetic retinopathy is significant for clinical diagnosis, early screening and course progression of patients. Methods
Zhitao Xiao, Xinpeng Zhang, Lei Geng, Fang Zhang, Jun Wu, Jun Tong, Philip O. Ogunbona, Chunyan Shan   +7 more
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Frequency of Diabetic Retinopathy in Karachi, Pakistan: A Hospital Based Study

Journal of the Dow University of Health Sciences, 2015
Objective: This study was conducted to determine the prevalence of diabetic retinopathy in diabetes patients presenting to the National Institute of Diabetes and Eye out patient department of Dow University Hospital (Ohja campus), Dow University of ...
saba Alkhairy, Abdul Rasheed, Farnaz Aziz, Mazhar ul Hassan, Sarfaraz Nawaz   +4 more
doaj   +4 more sources

Frequency of diabetic retinopathy in patients with diabetes mellitus and its correlation with duration of diabetes mellitus

Medical Journal of Dr. D.Y. Patil University, 2013
Purpose : To evaluate the correlation between diabetic retinopathy (DR) and duration of diabetes mellitus (DM). Materials and Methods : A cross-sectional study was carried out in 500 patients who were reported diabetics or newly diagnosed diabetics ...
Piyush Bansal, Rajendra P Gupta, Megha Kotecha   +2 more
doaj   +1 more source

Chrysin attenuates diabetes‐induced retinal injury by inhibiting microglial GBP3/NLRP3/GSDMD‐mediated pyroptosis

Animal Models and Experimental Medicine, EarlyView.
We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu, Song‐min Wang, Xuan Chen, Yi‐rao You, Chen‐jiao Guo, Chang‐qin Xie, Lu‐lu Wang, Qi Liu, Lan Zhang, Jun‐tao Yang   +9 more
wiley   +1 more source

Rates of referable eye disease in the Scottish National Diabetic Retinopathy Screening Programme [PDF]

, 2014
Aims: Diabetic retinopathy screening aims to detect people at risk of visual loss due to proliferative diabetic retinopathy, but also refers cases of suspected macular oedema (maculopathy).
Lee, N, Scottish Diabetes Research Network (SDRN) Epidemiology group, Wild, S H, Cromie, D T, Colhoun, H. M., Cromie, D. T., Wild, S. H., Morris, A D, Olson, J. A., Philip, Sam, McKnight, J. A., Pearson, D. W. M., Leese, G. P., Morris, Andrew, Lindsay, R.S., Lee, N., Olson, J A, Leese, G P, Wild, S. H.; id_orcid, Looker, H. C., Doig, J, Pearson, D W M, Black, M W, Looker, H C, Doig, J., ?, ?, Nyangoma, S. O., Black, M. W., Lindsay, R. S., Morris, A. D., Nyangoma, S O, Lindsay, R S, Philip, S., Colhoun, H M, McKnight, J A   +34 more
core   +1 more source

The unmet need for better risk stratification of non‐proliferative diabetic retinopathy [PDF]

Diabetic Medicine, 2018
AbstractDiabetic retinopathy is a common microvascular complication of diabetes and remains one of the leading causes of preventable blindness in working‐age people. Non‐proliferative diabetic retinopathy is the earliest stage of diabetic retinopathy and is typically asymptomatic.
S. Sivaprasad, E. Pearce
openaire   +2 more sources