Intra-rater Reliability and Criterion-related Validity of using an Accelerometer to Measure the Impact Force and Knee Joint Sway during Single-leg Drop Landing [PDF]
, 2019 学位記番号 ...
Okamoto, Shogo +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Study on Short Fatigue Crack Behaviour of LZ50 Steel Under Non-Proportional Loading. [PDF]
Materials (Basel), 2020 Yang B +5 more
europepmc +1 more source
Single cell mechanics: stress stiffening and kinematic hardening
, 2007 Cell mechanical properties are fundamental to the organism but remain poorly understood. We report a comprehensive phenomenological framework for the nonlinear rheology of single fibroblast cells: a superposition of elastic stiffening and viscoplastic ...
A. Mogilner +10 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fatigue Assessment of Rib–Deck Welded Joints in Orthotropic Steel Bridge Decks Under Traffic Loading
CivilEngRib–deck (RD) welded joints in orthotropic steel bridge decks are prone to different fatigue crack mechanisms. Standard fatigue design methods are inadequate for some of these mechanisms under multiaxial non-proportional loading conditions.
Bruno Villoria +2 more
doaj +1 more source
Self-organization without conservation: Are neuronal avalanches generically critical?
, 2010 Recent experiments on cortical neural networks have revealed the existence of well-defined avalanches of electrical activity. Such avalanches have been claimed to be generically scale-invariant -- i.e.
Bak P +16 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
RESEARCH ON MULTI-AXIAL FATIGUE LIFE OF CRANE WELD BASED ON STRUCTURAL STRESS METHOD
Jixie qiangdu, 2022 As an example of life evaluation of the weld between main girder and rigid leg of 580 t gantry crane based on structural stress method, the non-proportional stress characteristics of multi-axis are obtained by analyzing the working stress history of ...
WANG Xin +4 more
doaj