Results 51 to 60 of about 106,123 (269)
An alternative approach to critical PDEs
Electronic Journal of Differential Equations, 2017 In this article, we use an alternative method to prove the existence of an infinite sequence of distinct non-radial nodal G-invariant solutions for critical nonlinear elliptic problems defined in the whole the Euclidean space.
Nikos Labropoulos
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Non-existence of positive radial solution for semipositone weighted p-Laplacian problems
Electronic Journal of Differential Equations, 2015 We prove the non-existence of positive radial solution to a semipositone weighted $p$-Laplacian problem whenever the weight is sufficiently large. Our main tools are a Pohozaev type identity and a comparison principle.
Sigifredo Herron, Emer Lopera
doaj
Journal of Physics: Theories and Applications, 2017 Non-relativistic bound-energy of diatomic molecules determined by non-central potentials in five dimensional solution using AIM. Potential in five dimensional space consist of Kratzer’s potential for radial part and Tangent squared potential for angular ...
Agung Budi Prakoso, A Suparmi, C Cari
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
EPJ Web of Conferences, 2016 Non-empty space reading of Maxwell equations as local energy identities explains why a Coulomb field is carried rigidly by electrons in experiments. The analytical solution of the Poisson equation defines the sharp radial shape of charged elementary ...
Bulyzhenkov Igor E.
doaj +1 more source
Infinitely Many Radial and Non-Radial Solutions for a Class of Hemivariational Inequalities
Rocky Mountain Journal of Mathematics, 2005 This paper deals with the study of the following class of hemivariational inequalities: find \(u\in H^1(\mathbb R^N)\) such that \[ \int_{\mathbb R^N}(\nabla u\nabla w+uw)dx+\int_{\mathbb R^N}F^0_x(x,u(x);-w(x))dx\geq 0, \] for all \(w\in H^1(\mathbb R^N)\), where \(F^0\) stands for the generalized directional derivative in the sense of Clarke.
openaire +3 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source