Results 61 to 70 of about 186,089 (328)

The Effect of Baclofen on Alterations in the Sleep Patterns Induced by Different Stressors in Rats

Journal of Pharmacological Sciences, 2009
We have previously reported that sleep patterns are significantly affected by both physical and psychological stress induced by a communication box ; however, the mechanism by which stress alters sleep patterns was not established.
Ranji Cui, Bingjin Li, Katsuya Suemaru, Hiroaki Araki   +3 more
doaj   +1 more source

Mathematical Phase Model of Neural Populations Interaction in Modulation of REM/NREM Sleep

Mathematical Modelling and Analysis, 2016
Aim of the present study is to compare the synchronization of the classical Kuramoto system and the reaction - diffusion space time Landau - Ginzburg model, in order to describe the alternation of REM (rapid eye movement) and NREM (non-rapid eye movement)
Paolo Acquistapace, Anna P. Candeloro, Vladimir Georgiev, Maria L. Manca   +3 more
doaj   +1 more source

Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus [PDF]

, 2017
Dysfunction of the striatum is frequently associated with sleep disturbances. However, its role in sleep-wake regulation has been paid little attention even though the striatum densely expresses adenosine A2A receptors (A2ARs), which are essential for ...
Cherasse Yoan, d\u27Exaerde Alban de Kerchove, Dong Hui, Huang Zhi-Li, Lazarus Michael, Li Rui-Xi, Qu Wei-Min, Schiffmann Serge N, Wang Lu, Yang Su-Rong, Yuan Xiang-Shan   +10 more
core   +1 more source

Hypnotic and Sleep Quality–Enhancing Properties of Kavain in Sleep-Disturbed Rats

Journal of Pharmacological Sciences, 2009
The present study was performed to investigate the effects of kavain on the sleep-wake cycle in comparison with that of rilmazafone and diphenhydramine using sleep-disturbed rats.
Ryuki Tsutsui, Kazuaki Shinomiya, Yasuhiro Takeda, Yoshihito Obara, Yoshihisa Kitamura, Chiaki Kamei   +5 more
doaj   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A Multi-Class Automatic Sleep Staging Method Based on Long Short-Term Memory Network Using Single-Lead Electrocardiogram Signals

IEEE Access, 2019
To overcome the disadvantage of clinical manual sleep staging, a convenient, economical, and efficient multi-class automatic sleep staging method is proposed based on long short-term memory network (LSTM) using single-lead electrocardiogram signals. From
Yuhui Wei, Xia Qi, Huaning Wang, Zhian Liu, Gang Wang, Xiangguo Yan   +5 more
doaj   +1 more source

Antidepressant suppression of REM and spindle sleep impairs hippocampus-dependent learning and memory but fosters striatal-dependent strategies [PDF]

, 2011
REM sleep enhances hippocampus-dependent associative memory but has little impact on striatal-dependent procedural learning. Antidepressant medications like desipramine (DMI) inhibit rapid-eye-movement (REM) sleep but it is little understood how ...
Alain Watts, Gina Poe, Howard Gritton, Jamie Sweigart   +3 more
core   +1 more source

In search of sleep biomarkers of Alzheimer's disease: K-Complexes do not discriminate between patients with mild cognitive impairment and healthy controls [PDF]

, 2017
The K-complex (KC) is one of the hallmarks of Non-Rapid Eye Movement (NREM) sleep. Recent observations point to a drastic decrease of spontaneous KCs in Alzheimer's disease (AD).
Cordone, Susanna, D\u2019Atri, Aurora, De Gennaro, Luigi, Ferrara, Michele, Gorgoni, Maurizio, Lacidogna, Giordano, Lauri, Giulia, Mangiaruga, Anastasia, Marra, Camillo (ORCID:0000-0003-3994-4044), Reda, Flaminia, Rossini, Paolo Maria (ORCID:0000-0003-2665-534X), Scarpelli, Serena, Truglia, Ilaria   +12 more
core   +2 more sources

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source