Exposure to sedative/hypnotic and anesthetic drugs, such as ketamine, during the critical period of synaptogenesis, causes profound neurotoxicity in the developing rodent and primate brains and is associated with poor cognitive outcomes later in life ...
Francesca M. Manzella +15 more
doaj +1 more source
Delta sleep instability in children with chronic arthritis [PDF]
The objective of the present study was to evaluate the expression of a cyclic alternating pattern (CAP) in slow wave sleep (SWS) in children with the well-defined chronic syndrome juvenile idiopathic arthritis (JIA).
Guilleminault, Christian +5 more
core +1 more source
Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi +12 more
wiley +1 more source
The retinal ipRGC-preoptic circuit mediates the acute effect of light on sleep
The preoptic area (POA) is critical for sleep regulation but its role in acute, non-circadian, light effects on sleep are unclear. The authors show that intrinsically photosensitive retinal ganglion cells provide substantial input into the POA and ...
Ze Zhang +3 more
doaj +1 more source
NREM and REM sleep parasomnias: clinical cases and literature review
Parasomnias are a group of sleep disorders that manifest as abnormal behaviour or movements while falling asleep, during sleep, or before awakening. According to the International Classification of Sleep Disorders (ICSD-3), parasomnias are subdivided ...
K. Teišerskytė +2 more
doaj +1 more source
Daytime Sleep Enhances Consolidation of the Spatial but Not Motoric Representation of Motor Sequence Memory [PDF]
Motor sequence learning is known to rely on more than a single process. As the skill develops with practice, two different representations of the sequence are formed: a goal representation built under spatial allocentric coordinates and a movement ...
Albouy, Geneviève +8 more
core +3 more sources
Hemodynamic cerebral correlates of sleep spindles during human non-rapid eye movement sleep [PDF]
In humans, some evidence suggests that there are two different types of spindles during sleep, which differ by their scalp topography and possibly some aspects of their regulation. To test for the existence of two different spindle types, we characterized the activity associated with slow (11–13 Hz) and fast (13–15 Hz) spindles, identified as discrete ...
Schabus, Manuel +16 more
openaire +3 more sources
Continual Learning for Multimodal Data Fusion of a Soft Gripper
Models trained on a single data modality often struggle to generalize when exposed to a different modality. This work introduces a continual learning algorithm capable of incrementally learning different data modalities by leveraging both class‐incremental and domain‐incremental learning scenarios in an artificial environment where labeled data is ...
Nilay Kushawaha, Egidio Falotico
wiley +1 more source
Decrease in REM latency and changes in sleep quality parallel serotonergic damage and recovery after MDMA: a longitudinal study over 180 days [PDF]
The recreational drug ecstasy [3,4-methylenedioxymethamphetamine (MDMA)], has been found to selectively damage brain serotonin neurons in experimental animals, and probably in human MDMA users, but detailed morphometric analyses and parallel ...
Adrien +22 more
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source

