Results 51 to 60 of about 595,021 (308)

High density genotype storage for plant breeding in the Chado schema of Breedbase.

open access: yesPLoS ONE, 2020
Modern breeding programs routinely use genome-wide information for selecting individuals to advance. The large volumes of genotypic information required present a challenge for data storage and query efficiency. Major use cases require genotyping data to
Nicolas Morales   +6 more
doaj   +1 more source

Improving the Deductive System DES with Persistence by Using SQL DBMS's [PDF]

open access: yes, 2015
This work presents how persistent predicates have been included in the in-memory deductive system DES by relying on external SQL database management systems.
Sáenz-Pérez, Fernando
core   +4 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

open access: yesAdvanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram   +10 more
wiley   +1 more source

Multi-objective database queries in combined knapsack and set covering problem domains

open access: yesJournal of Big Data, 2021
Database queries are one of the most important functions of a relational database. Users are interested in viewing a variety of data representations, and this may vary based on database purpose and the nature of the stored data.
Sean A. Mochocki   +3 more
doaj   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

open access: yesAdvanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao   +6 more
wiley   +1 more source

Design and Implementation of Relation Database and Non-Relation Database Unified Query Model

open access: yesAdvances in Intelligent Systems Research, 2014
For scenarios that application data stored separately in relational database and non-relational database, an establishment of a unified query abstraction layer for SQL and NoSQL database is proposed, which can query data from different database as from a single data source.
Naizheng Bian, Xiaoyu Zheng
openaire   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

open access: yesAdvanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi   +4 more
wiley   +1 more source

Enhancement of database access performance by improving data consistency in a non-relational database system (NoSQL)

open access: yes, 2023
<p>This study aims to enhance data consistency in NoSQL databases, traditionally designed with BASE properties, as opposed to the strong consistency guaranteed by ACID principles in RDBMS. We introduce a comprehensive four-stage server-side model engineered explicitly for MongoDB.
Adam A. E. Alflahi   +2 more
openaire   +2 more sources

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Bio-Strings: A Relational Database Data-Type for Dealing with Large Biosequences

open access: yesBioTech, 2022
DNA sequencers output a large set of very long biological data strings that we should persist in databases rather than basic text file systems. Many different data models and database management systems (DBMS) may deal with both storage and efficiency ...
Sergio Lifschitz   +7 more
doaj   +1 more source

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