Results 231 to 240 of about 10,270,570 (295)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Misdiagnosis of restrictive cardiomyopathy averted by a stethoscope: a case report. [PDF]

open access: yesEur Heart J Case Rep
Kothari SS   +4 more
europepmc   +1 more source

Prevalence of Cystic Fibrosis and Pattern of Lung Function Impairment in Adults Presenting With Bronchiectasis at a Tertiary Care Hospital in Resource Poor Country Bangladesh: A Cross-Sectional Study. [PDF]

open access: yesHealth Sci Rep
Majumder S   +12 more
europepmc   +1 more source

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