Results 1 to 10 of about 7,675 (152)

Treatment of clinical stage I non-seminoma [PDF]

Asian Journal of Urology, 2021
Germ cell cancers are the most common solid tumors among men between 15 and 40 years. Non-seminomatous germ cell tumors (NSGCTs) represent a unique and exclusive cohort of germ cell tumor patients. Non-seminoma can harbor different histologic components.
Christian Winter, Andreas Hiester
doaj   +4 more sources

Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours [PDF]

Epigenetics, 2021
Testicular germ cell tumours (TGCTs) are the most common cancer in young male adults (aged 15 to 40). Unlike most other cancer types, identification of molecular signatures in TGCT has rarely reported.
Saurav Mallik, Guimin Qin, Peilin Jia, Zhongming Zhao   +3 more
doaj   +3 more sources

ANN as a prognostic tool after treatment of non-seminoma testicular cancer

Open Medicine, 2012
Abstract Testicular cancer is rare but is the most common cancer in males between 15 and 34 years of age. Two principal types of testicular cancer are distinguished: seminomas and non-seminomas. If detected early, the overall cure rate for testicular cancer exceeds 90%.
Marszałł Michał, Krysiński Jerzy, Sroka Wiktor, Nyczak Zbigniew, Stefanowicz Marek, Waśniewski Tomasz, Romaszko Jerzy, Buciński Adam   +7 more
doaj   +3 more sources

Deep learning-based super-resolution US radiomics to differentiate testicular seminoma and non-seminoma: an international multicenter study [PDF]

Insights into Imaging
Objectives Subvariants of testicular germ cell tumor (TGCT) significantly affect therapeutic strategies and patient prognosis. However, preoperatively distinguishing seminoma (SE) from non-seminoma (n-SE) remains a challenge. This study aimed to evaluate
Yafang Zhang, Shilin Lu, Chuan Peng, Shichong Zhou, Irene Campo, Michele Bertolotto, Qian Li, Zhiyuan Wang, Dong Xu, Yun Wang, Jinshun Xu, Qinfu Wu, Xiaoying Hu, Wei Zheng, Jianhua Zhou   +14 more
doaj   +2 more sources

The value of the “map sign” in shear wave elastography for differentiating seminomas from non-seminomas [PDF]

BMC Medical Imaging
Background Diagnosing testicular tumors that are negative for tumor markers using ultrasound and MRI is currently challenging. Seminomas and non-seminomas of the testis have different clinical diagnoses and treatment plans.
Shanshan Liu, Zixia Zhou, Nianyu Xue
doaj   +2 more sources

Pharmacological WEE1 inhibition as a strategy to overcome cisplatin resistance in non-seminoma testicular cancer: insights from preclinical models [PDF]

Scientific Reports
Testicular germ cell tumors are the most common solid malignancy in young adult males with non-seminomatous representing a clinically aggressive subtype.
Mariangela Tamburello, Caterina Boldini, Andrea Abate, Valentina Salvi, Francesca Valcamonico, Marta Laganà, Deborah Cosentini, Nazareno R. Suardi, Giuseppe Mirabella, Barbara Altieri, Sandra Sigala   +10 more
doaj   +2 more sources

Primary extragonadal germ cell tumours: Real‐world data from a high‐volume centre [PDF]

BJUI Compass
Objectives To provide improved evidence for treatment recommendations, this study analysed real‐world data on the characteristics, treatment and prognosis of primary extragonadal germ cell tumours (EGCTs), a very rare cancer entity that shares ...
Marc Kidess, Marcus Hentrich, Franz Aschl, Oksana Chernova, Sebastian Beckstein, Peter Bojko, Sebastian Schulz, Julia Neitz, Julian Hermans, Yannic Volz, Benedikt Ebner, Patrick Keller, Maria Apfelbeck, Julian Marcon, Philipp Weinhold, Christian G. Stief, Lennert Eismann, Michael Chaloupka   +17 more
doaj   +2 more sources

A Rare Case of Testosterone-Producing Non-Seminoma Germ-Cell Testicular Cancer. [PDF]

JCEM Case Rep
Abstract Androgen secretion by testicular germ-cell tumors (GCTs) appears to be markedly rare and likely underreported in the literature. This case study highlights a patient with such a rare tumor, underscoring a notable and yet easily avoidable diagnostic oversight in one of the most prevalent cancers among men.
Mänd SÅ, Sjöholm Å.
europepmc   +5 more sources

A pure intertubular testicular seminoma mimicking a burned-out tumor: a case report [PDF]

Frontiers in Oncology
BackgroundIn men presenting with metastatic seminoma and no discrete intratesticular mass, multiparametric MRI (mpMRI) findings such as atrophy, heterogeneity, calcifications, and focal low-signal areas are often interpreted as a regressed (“burned-out”)
Vassiliki Pasoglou, Sandy Van Nieuwenhove, Hélène Dano, Brieuc Sautois, Laurence Rocher, Julien Van Damme, Bertrand Tombal, Emmanuel Seront   +7 more
doaj   +2 more sources

Distinct telomere length and molecular signatures in seminoma and non-seminoma of testicular germ cell tumor. [PDF]

Brief Bioinform, 2019
Sun H, Kim P, Jia P, Park AK, Liang H, Zhao Z.   +5 more
europepmc   +2 more sources