Results 151 to 160 of about 109,707 (304)
Diabetic Medicine, EarlyView.Abstract Aims Despite intensive lipid‐lowering therapy, individuals with atherosclerotic cardiovascular disease (ASCVD) exhibit residual inflammatory risk, which drives recurrent cardiovascular events. This risk is amplified in type 2 diabetes mellitus (T2DM), where a pro‐inflammatory milieu accelerates atherogenesis. Monocyte‐derived macrophages (MDMs)
J. K. Ward +4 more
wiley +1 more source
An oral glucose tolerance test in pregnancy and its association with future cardiovascular diseases
Diabetes, Obesity and Metabolism, EarlyView.Abstract Aims/hypothesis Gestational diabetes and abnormal 100‐g oral glucose tolerance test (OGTT) results in pregnancy are associated with type 2 diabetes, but their relationship with cardiovascular disease (CVD) is less clear. We evaluated the risk of CVD according to the number of abnormal OGTT values during pregnancy.
Tal Schiller +7 more
wiley +1 more source
Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression
The FEBS Journal, EarlyView.T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera +5 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow +3 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood +4 more
wiley +1 more source
Internal Medicine Journal, EarlyView.ABSTRACT Background Longitudinal data on in‐hospital glycaemia from Australian hospitals are limited. Aims: The aim of this study was to evaluate the efficacy and safety of current inpatient management strategies in New South Wales hospitals and to compare hospital‐acquired complication (HAC) rates in patients with and without diabetes.
Barbara Depczynski +2 more
wiley +1 more source
Nemolizumab in prurigo nodularis up to 100 weeks: OLYMPIA LTE interim analysis
Journal of the European Academy of Dermatology and Venereology, EarlyView.In this interim analysis of the OLYMPIA long‐term extension trial, nemolizumab exhibited sustained efficacy and was well tolerated through 100 weeks, with most adverse events being mild/moderate. Patients showed clinically meaningful improvements in core signs and symptoms.
Franz J. Legat +22 more
wiley +1 more source
When Delirium Unmasks a Silent Myocardial Infarction
Journal of the American Geriatrics Society, EarlyView.Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali +10 more
wiley +1 more source