Sleep Deprivation Alters T Cell Dynamics: Melatonin as a Restorative Agent
Journal of Sleep Research, EarlyView.ABSTRACT Sleep is an essential physiological function regulated by circadian rhythm and homeostatic regulation for emotional and physical health. Conversely, sleep deprivation (SD) is associated with weakened immune system function and overall health, which potentially leads to chronic diseases such as heart disease and diabetes.
Hilal Öztürk +8 more
wiley +1 more source
Treatment Trade‐Offs and Choices for Femoral Fractures: A Systematic Review and Meta‐Analysis
Orthopaedic Surgery, Volume 17, Issue 5, Page 1298-1313, May 2025.This review examines the trade‐offs between surgical intervention and traction therapy for adult and elderly patients with femoral fractures and surgical contraindications, particularly in resource‐limited settings. While intramedullary nailing may offer better clinical outcomes, traction therapy is often preferred due to limited surgical resources ...
Jiarui Li +11 more
wiley +1 more source
EuroSCORE II: Current limitations and physiological gaps in risk stratification
Experimental Physiology, EarlyView.Abstract Risk stratification remains critical in cardiac surgery, enabling clinicians to predict adverse outcomes and guide perioperative management. The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, introduced in 2011, incorporates 18 key variables to provide an evidence‐based approach to risk assessment.
Jing Yong Ng +7 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Acute myocardial infarction is a leading cause of morbidity and mortality, with ischaemia–reperfusion (I/R) injury exacerbating myocardial damage. Vagus nerve stimulation (VNS) has been reported to exert cardioprotective effects, but its efficacy in preconditioning against I/R injury requires further investigation.
Feng Hu +10 more
wiley +1 more source
One ECG with 2 Rare Findings: Wellens Syndrome With Prolonged QT Interval in Acute Myocardial Infarction Due to LAD Occlusion. [PDF]
Am J Case RepBryndza M +5 more
europepmc +1 more source
Non-ST-elevation myocardial infarction complicating carcinoid syndrome [PDF]
Cardiovascular Disorders and Medicine, 2017 Ayman Elbadawi +4 more
openaire +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, EarlyView.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
Clinical and pathophysiological significance of circ-0049271 in acute ST-segment elevation myocardial infarction. [PDF]
J Int Med ResLiao H, Xiao C, Li W, Xiang D.
europepmc +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
The Journal of Physiology, EarlyView.Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source