Results 21 to 30 of about 55,364 (213)

Structure, Process, and Mortality Associated with Acute Coronary Syndrome Management in Guatemala’s National Healthcare System: The ACS-GT Registry

Global Heart, 2022
Background: Acute coronary syndromes (ACS) include ST-segment elevation myocardial infarction (STEMI), non-ST-segment elevation myocardial infarction (NSTEMI), and unstable angina (UA).
José Antonio Cornejo-Guerra, Magda Isabel Ramos-Castro, Mariana Gil-Salazar, Sofia Leal-Wittkowsky, Juan Carlos Santis-Mejía, Elisa María Anleu-De León, Oscar Fernando Castro-Alvarado, Boris Rudy Alexander López-Quiñónez, Edgar Alexander Illescas-González, Paola Overall-Salazar, Luis Antonio Rodríguez-Cifuentes, Karla Yesenia Miranda-Sandoval, Juan Pablo Pineda, Kevin Oneal Flores-Andrade, Roberto Antonio Pérez-Reyes, Sofía Waleska Girón-Blas, Josué Fernando Samayoa-Ruano   +16 more
doaj   +1 more source

Short‐Term Exposure to Fine Particulate Matter Air Pollution Is Preferentially Associated With the Risk of ST‐Segment Elevation Acute Coronary Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Air pollution is associated with greater cardiovascular event risk, but the types of events and specific persons at risk remain unknown. This analysis evaluates effects of short‐term exposure to fine particulate matter air pollution with risk ...
C. Arden Pope III, Joseph B. Muhlestein, Jeffrey L. Anderson, John B. Cannon, Nicholas M. Hales, Kent G. Meredith, Viet Le, Benjamin D. Horne   +7 more
doaj   +1 more source

Non-ST elevation myocardial infarction secondary to carbon monoxide intoxication

Journal of Community Hospital Internal Medicine Perspectives, 2017
Carbon monoxide poisoning has been documented in literature to cause severe neurological and tissue toxicity within the body. However, cardiotoxicity is often overlooked, but not uncommon.
Danuta Jankowska, Venkataraman Palabindala, Sohail Abdul Salim   +2 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

A Case of Acute Myocardial Injury – MINOCA or Myocarditis?

Journal of Interdisciplinary Medicine, 2020
Myocardial infarction with non-obstructive coronary arteries (MINOCA) has been defined as clinical presentation of an acute coronary syndrome with laboratory evidence of myocardial necrosis, but with coronary stenosis of less than 50% on coronary ...
Libenciuc Camelia, Licu Răzvan-Andrei, Kovacs Istvan, Chitu Monica, Benedek Imre   +4 more
doaj   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Differential diagnosis of myocardial infarction and myopericarditis during a pandemic

Медицинский совет, 2021
Difficulties in the differential diagnosis of non-ST-elevation myocardial infarction (NSTEMI) and acute myopericarditis during the novel coronavirus infection (COVID-19) pandemic appear to be a relevant and interesting issue.We present a clinical case of
E. V. Konstantinova, M. R. Atabegashvili, A. A. Savicheva, A. P. Nesterov, M. Yu. Gilyarov   +4 more
doaj   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Cellular Mechanisms Enabling Mitochondria Transfer and Transplantation

Advanced Science, EarlyView.
Mitochondrial transfer and transplantation (mitoTT) is examined as a multistep process governed by distinct transfer routes and post‐transfer checkpoints. Mechanisms controlling mitochondrial uptake, network integration, cristae remodeling, mtDNA maintenance, immune sensing, and quality control are highlighted, revealing key biological and ...
F. Seyma Gokdemir, Yagmur Ozendi, Gokhan Burcin Kubat, Keshav K. Singh   +3 more
wiley   +1 more source