Results 41 to 50 of about 12,832,564 (302)

The effect of hydroxychloroquine on cholesterol metabolism in statin treated patients after myocardial infarction

Atherosclerosis Plus, 2023
Background and aims: To evaluate the effect of hydroxychloroquine (HCQ) on serum and lipoprotein lipids and serum biomarkers of cholesterol synthesis and absorption in myocardial infarction patients with a high-dose statin. Methods: Myocardial infarction
Lotta Ulander, Piia Simonen, Heli Tolppanen, Otto Hartman, Tuomas T. Rissanen, Kari K. Eklund, Marita Kalaoja, Mika Kurkela, Mikko Neuvonen, Mikko Niemi, Janne T. Backman, Helena Gylling, Juha Sinisalo   +12 more
doaj   +1 more source

Short-term and long-term outcomes in 133 429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990-2000: population-based cohort study [PDF]

, 2006
Objective: To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency admission for suspected acute coronary syndrome between 1990 and 2000 in Scotland. Methods: All
Frame, S., Boyd, J., Redpath, A., K MacIntyre, A Finlayson, A Redpath, S Capewell, J Boyd, Capewell, S., MacIntyre, K., Stewart, S., J W T Chalmers, Chalmers, J.W.T., N F Murphy, S Frame, S Stewart, Murphy, N.F., McMurray, J.J.V., J J V McMurray, Finlayson, A.   +19 more
core   +1 more source

Association between clinical presentations before myocardial infarction and coronary mortality: a prospective population-based study using linked electronic records. [PDF]

, 2014
BACKGROUND: Ischaemia in different arterial territories before acute myocardial infarction (AMI) may influence post-AMI outcomes. No studies have evaluated prospectively collected information on ischaemia and its effect on short- and long-term coronary ...
Hemingway, Harry, Herrett, Emily, Smeeth, Liam, Bhaskaran, Krishnan, Denaxas, Spiros, Timmis, Adam   +5 more
core   +1 more source

Are There Options to Prevent Early Occurring Deaths in Acute Myocardial Infarction: Prospective Evaluation of All < 24 h In-Hospital Deaths, 2004-2006-The MONICA/KORA Augsburg Infarction Registry [PDF]

, 2010
Objectives: To provide valid clinical data of early in-hospital deaths with presumed acute myocardial infarction (AMI) who are often not included in clinical trials or registries.
Kuch, B., Kuch, Bernhard, von Scheidt, W., Anja Ehmann, Greschik, C., Ehmann, Anja, Birgitt Kling, Scheidt, Wolfgang von, Kling, Birgitt, Kling, B., Bernhard Kuch, Meisinger, Christa, Wolfgang von Scheidt, Claudia Greschik, Ehmann, A., Greschik, Claudia, Christa Meisinger, von Scheidt, Wolfgang, Meisinger, C.   +18 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

Advanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao, Zimeng Huang, Jianing Gao, Aolan Li, Huizhi Wang, Yingchuan Chen, Guanyu Zhu, Xin Zhang, Yin Jiang, Moxuan Zhang, Fangang Meng, Jianguo Zhang, Tingting Du   +12 more
wiley   +1 more source

Short‐Term Exposure to Fine Particulate Matter Air Pollution Is Preferentially Associated With the Risk of ST‐Segment Elevation Acute Coronary Events

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Air pollution is associated with greater cardiovascular event risk, but the types of events and specific persons at risk remain unknown. This analysis evaluates effects of short‐term exposure to fine particulate matter air pollution with risk ...
C. Arden Pope III, Joseph B. Muhlestein, Jeffrey L. Anderson, John B. Cannon, Nicholas M. Hales, Kent G. Meredith, Viet Le, Benjamin D. Horne   +7 more
doaj   +1 more source

Validation of TIMI risk score for STEMI patients visiting a tertiary care hospital of western Nepal

Journal of Gandaki Medical College, 2022
Introduction: Cardiovascular disease is the leading cause of death globally, and ST elevation myocardial infarction remains main contributor to this mortality.
Ram Chandra Kafle, Dibya Sharma, Daya Ram Pokharel   +2 more
doaj   +1 more source

Particularities of non-ST-elevation myocardial infarction in women

Bulletin of the Academy of Sciences of Moldova. Medical Sciences, 2022
Despite the fact that women have lower incidence of non-ST-elevation myocardial infarction (NSTEMI) compared with men, they have a higher mortality, attributed to the impact of the age, higher burden of comorbidities, atypical symptoms and possible differences in the diagnosis and treatment of NSTEMI.
Olga Dicusar, Mihaela Ivanov, Carolina Dumanskhii, Stela Fuior, Natalia Litvinenco, Victoria Ivanov, Lucia Ciobanu, Mihail Popovici   +7 more
openaire   +1 more source

Bivalirudin started during emergency transport for primary PCI. [PDF]

, 2013
BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).
Prats, Jayne, Grunsven, P. van, Zeymer, U., Pocock, Stuart, Campo dell' Orto, Marco, Huber, K., Clemmensen, Peter, Bernstein, D., Goldstein, Patrick, Coste, Pierre, Zeymer, Uwe, Clayton, T., Prats, J., Hamm, C.W., Orto, M. Campo dell', Clayton, Tim, Orto, Marco Campo Dell', Soulat, Louis, Deliargyris, E.N., Eggink, G.J., Hamon, Martial, et al., Bernstein, Debra, Eggink, Gerrit Jan, Steinmetz, Jacob, Nibbe, Lutz, Investigators, the EUROMAX, Berg, Jurrien Ten, Pocock, S., Mikkelsen, Søren; id_orcid, Steg, Philippe Gabriel, EUROMAX Investigators, Deliargyris, Efthymios N, Schuette, Diana, Berg, J. van den, Verheugt, F.W.A., Schuette, D., Soulat, L., Van Grunsven, Pierre, Nef, Holger, Coste, P., Huber, Kurt, Hamon, M., Hof, A. van't, Goldstein, P., Steinmetz, J., Lapostolle, F., Nibbe, L., Lapostolle, Frédéric, Nef, H., Hamm, Christian W, Steg, P.G., van 't Hof, Arnoud, Ten Berg, Jurrien, Clemmensen, P.   +54 more
core   +1 more source