Results 131 to 140 of about 26,546,882 (300)
This chapter surveys the discourse on the application, interpretation, developments and controversies in relation to the role of non-State actors and warfare. The aim of the chapter is to summarize the main legal issues that arise when assessing the role of non-State actors in warfare, identifying how developments in the armed conflicts in Ukraine and ...
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Pre-Analysis Plan: Political support by non-state actors for non-state actors
Please see the attached file for the Pre-Analysis Plan of the research project: Political support by non-state actors for non-state actors. It includes background information, conceptualization, research design, hypotheses, data collection, its ethics ...
Sara Daub
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The recent attack in Russia by the ISIS-Khorasan and the killing of 150 Russians has sparked international eyeballs. The act is condemned by the international community. Different views have been expressed about this attack and its political implications.
Gupta, Biswanath, Mehrotra, Abhinav
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The communication by States of International Law to their direct stakeholders
ACDI: Anuario Colombiano de Derecho Internacional, 2010 From the beginning International law has been conceived as beingbetween states. However, as a result of the progressive development of the law, new actors and new subjects have taken root.
Ilias Bantekas
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Right to health and social justice in Bangladesh: ethical dilemmas and obligations of state and non-state actors to ensure health for urban poor. [PDF]
BMC Med Ethics, 2018 Shafique S +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source