Results 141 to 150 of about 1,099,174 (311)
PolitejaFAITH-BASED DIPLOMACY NON-STATE ACTORS IN THE PEACE PROCESS – THE EXAMPLE OF THE ACHOLI RELIGIOUS LEADERS PEACE INITIATIVE Parallel to the actors of classical diplomacy, non-state actors are engaged in efforts to restore peace. A particular category
Michał J. Nadziak +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Journal of Islamic World and PoliticsIsrael's atrocities against the people of Palestine in Gaza have entered an unprecedented stage through acts of genocide. Moreover, America's partiality towards Israel has an impact on the reluctance of other state actors to intervene deeply.
Khairul Munzilin, Elyana Ade Pertiwi
doaj +1 more source
The International Bar Association and Trade in Legal Services: Meta Law-Making in International Economic Law? [PDF]
, 2019 This article presents the International Bar Association as a highly-influential but often overlooked non-state actor through the lens of its involvement in the standardization of Mutual Recognition Agreements (MRA)s for legal services.
Collins, D. A.
core
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The communication by States of International Law to their direct stakeholders
ACDI: Anuario Colombiano de Derecho Internacional, 2010 From the beginning International law has been conceived as beingbetween states. However, as a result of the progressive development of the law, new actors and new subjects have taken root.
Ilias Bantekas
doaj
From state to non-state actors: The emergence of security governance [PDF]
, 2005 Krahmann, E
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source