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Conjugation of Steroidal and Non – Steroidal Anti- Inflammatory Drugs as Possible Mutual Prodrug
Prednisolone (SAID) was conjugated with ibuprofen (NSAID) through an amino acid (glycine) as a spacer arm to synthesize the following compound: Prednisolone – glycine – ibuprofen.
Muthanna D. Saud
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Low-Dose Tramadol and Non-Steroidal Anti-Inflammatory Drug Combination Therapy Prevents the Transition to Chronic Low Back Pain [PDF]
Study DesignRetrospective study.PurposeTo determine whether low-dose tramadol plus non-steroidal anti-inflammatory drug combination therapy could prevent the transition of acute low back pain to chronic low back pain.Overview of LiteratureInadequately ...
Kazuhide Inage+17 more
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Steroidal and non-steroidal mineralocorticoid receptor antagonists in cardiorenal medicine
This review covers the last 80 years of remarkable progress in the development of mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first mineralocorticoid to trials of nonsteroidal MRAs.
R. Agarwal+6 more
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Non-Steroidal Antiinflammatory Drugs [PDF]
1. Non-steroidal antiinflammatory drugs (NSAIDs) are among the most frequently prescribed medications and are used primarily to control pain, stiffness, and reduce inflammation. 2. One of the most common adverse effects of NSAID therapy is gastrointestinal (GI) problems, specifically indigestion, nausea, dyspepsia, diarrhea, constipation, and gastritis.
Frances Childre+2 more
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Psoriatic arthritis: A retrospective study of 162 patients [PDF]
Aim. The aim of our study was to determine the prevalence of psoriatic arthritis in the patients with psoriasis and to analyze retrospectively the results of a 34-year multidisciplinary management of the patients with psoriatic arthritis. Methods.
Pavlica Ljiljana+4 more
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Non‐steroidal anti‐inflammatory drugs, prostaglandins, and COVID‐19
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the cause of the novel coronavirus disease 2019 (COVID‐19), a highly pathogenic and sometimes fatal respiratory disease responsible for the current 2020 global pandemic.
C. Robb+3 more
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Non-steroidal anti-inflammatory drugs for acute low back pain.
BACKGROUND Acute low back pain (LBP) is a common health problem. Non-steroidal anti-inflammatory drugs (NSAIDs) are often used in the treatment of LBP, particularly in people with acute LBP.
Wendelien van der Gaag+4 more
semanticscholar +1 more source
Background/Aims: The incidence of peptic ulcer disease has decreased in past decades; however, the trends in peptic ulcer bleeding (PUB) are inconsistent among regions.
Yong Sung Kim+5 more
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Non-steroidal drug-induced glaucoma [PDF]
Numerous systemically used drugs are involved in drug-induced glaucoma. Most reported cases of non-steroidal drug-induced glaucoma are closed-angle glaucoma (CAG). Indeed, many routinely used drugs that have sympathomimetic or parasympatholytic properties can cause pupillary block CAG in individuals with narrow iridocorneal angle.
Michael J. Pro+2 more
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Non Steroidal Anti-Inflammatory Drugs and Inflammatory Bowel Disease
Inflammatory Bowel Diseases (IBD) are an immune mediated chronic or relapsing disorders of the gastrointestinal (GI) tract. IBD is characterized by a chronic intestinal inflammatory process with various components contributing to the pathogenesis of the ...
Amir Klein, Rami Eliakim
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