Results 1 to 10 of about 9,749,992 (340)

Topical non-steroidal immunomodulators in dermatology [PDF]

open access: yesIndian Dermatology Online Journal, 2023
Immunological abnormality is the pathological basis of many dermatological disorders. Although steroids are the backbone of topical therapy in dermatology, the side effects are encountered quite frequently.
Priya P Kadu
doaj   +4 more sources

Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment. [PDF]

open access: yesJ Med Chem, 2023
CYP17A1 is an enzyme that plays a major role in steroidogenesis and is critically involved in the biosynthesis of steroid hormones. Therefore, it remains an attractive target in several serious hormone-dependent cancer diseases, such as prostate cancer and breast cancer.
Wróbel TM   +6 more
europepmc   +6 more sources

Pharmacoepidemiology of non-steroidal anti-inflammatory drugs [PDF]

open access: yesTherapies, 2019
Non-steroidal anti-inflammatory drugs (NSAIDs) are reversible inhibitors of cyclo-oxygenase (COX), mainly used for the symptomatic relief of pain, whether traumatic, infectious, episodic or rheumatologic. Use for the long-term relief of inflammation is waning with the emergence of specific biotherapies. Their effects are related to potency, dosage, and
Moore, Nicholas   +4 more
openaire   +6 more sources

OSTEOARTHRITIS—ANALGESICS OR NON-STEROIDALS?

open access: goldJournal of Clinical Pharmacy and Therapeutics, 1989
R. W. Jubb
openalex   +4 more sources

Effects of aromatase inhibitors on the ocular surface microenvironment [PDF]

open access: yesGuoji Yanke Zazhi, 2023
AIM: To analyze the effects of aromatase inhibitors(AIs)on the ocular surface microenvironment of the users.METHODS: A cross-sectional observational study was conducted.
Peng Xu   +3 more
doaj   +1 more source

Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network meta-analysis

open access: yesBritish medical journal, 2021
Objective To assess the effectiveness and safety of different preparations and doses of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip osteoarthritis pain and physical function to enable effective and safe use ...
B. D. da Costa   +17 more
semanticscholar   +1 more source

Novel non‐steroidal mineralocorticoid receptor antagonists in cardiorenal disease

open access: yesBritish Journal of Pharmacology, 2021
Mineralocorticoid receptor antagonists (MRAs) are key agents in guideline‐oriented drug therapy for cardiovascular diseases such as chronic heart failure with reduced ejection fraction and resistant hypertension.
U. Kintscher, G. Bakris, P. Kolkhof
semanticscholar   +1 more source

Non-steroidal anti-inflammatory drugs and the gastrointestinal tract.

open access: yesClinical medicine (London), 2021
Non-steroidal anti-inflammatory drugs (NSAIDs) are used commonly but can cause foregut symptoms, peptic ulcer disease and small bowel enteropathy. Such iatrogenic injury can be complicated by gastrointestinal bleeding and perforation.
F. Tai, M. McAlindon
semanticscholar   +1 more source

The effect of rebamipide on non-steroidal antiinflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2022
Background/Aims Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers.
Dong Jun Oh   +13 more
doaj   +1 more source

Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review

open access: yesBiomolecules, 2021
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used classes of medicines in the treatment of inflammation, fever, and pain. However, evidence has demonstrated that these drugs can induce significant toxicity.
G. M. Miranda   +6 more
semanticscholar   +1 more source

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