Results 1 to 10 of about 10,146,697 (338)
Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment [PDF]
Journal of Medicinal Chemistry, 2023 CYP17A1 is an enzyme that plays a major role in steroidogenesis and is critically involved in the biosynthesis of steroid hormones. Therefore, it remains an attractive target in several serious hormone-dependent cancer diseases, such as prostate cancer ...
Tomasz M. Wróbel +6 more
semanticscholar +5 more sources
Recent Advances in Hepatotoxicity of Non Steroidal Anti-inflammatory Drugs
Annals of Hepatology, 2018 Non-steroidal-anti-inflammatory drugs (NSAIDs) make a heterogenous pharmaco-therapeutic class of drugs among the most used drugs worldwide with various indications, modes of administration and increasing automedication.
Lucy Meunier, Dominique Larrey
doaj +2 more sources
Non-steroidal Anti-inflammatory Drug Prescriptions in Living Kidney Donors: A Retrospective Cohort Study [PDF]
Canadian Journal of Kidney Health and DiseaseBackground: Current guidelines recommend that living kidney donors should avoid non-steroidal anti-inflammatory drugs due to their potential nephrotoxic effects. It is unclear if physicians are adhering to this recommendation.
Mikayla I. Laube +7 more
doaj +2 more sources
Cureus, 2023 Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for their anti-inflammatory, antipyretic, and analgesic properties. However, their use is often associated with gastrointestinal tract (GIT) side effects due to the inhibition of both ...
Rohab Sohail +9 more
semanticscholar +1 more source
British medical journal, 2021 Objective To assess the effectiveness and safety of different preparations and doses of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip osteoarthritis pain and physical function to enable effective and safe use ...
Bruno R. da Costa +17 more
semanticscholar +1 more source
The effect of rebamipide on non-steroidal antiinflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers.
Dong Jun Oh +13 more
doaj +1 more source
Non-steroidal anti-inflammatory drugs and the gastrointestinal tract.
Clinical medicine (London), 2021 Non-steroidal anti-inflammatory drugs (NSAIDs) are used commonly but can cause foregut symptoms, peptic ulcer disease and small bowel enteropathy. Such iatrogenic injury can be complicated by gastrointestinal bleeding and perforation.
F. Tai, M. McAlindon
semanticscholar +1 more source
Inclusion Complexes of Non-Steroidal Anti-Inflammatory Drugs with Cyclodextrins: A Systematic Review
Biomolecules, 2021 Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used classes of medicines in the treatment of inflammation, fever, and pain. However, evidence has demonstrated that these drugs can induce significant toxicity.
G. M. Miranda +6 more
semanticscholar +1 more source
SAGE Open Medicine, 2022 This systematic review aimed to evaluate the efficacy of different non-steroidal anti-inflammatory drugs therapy (monotherapy or combined with antibiotics) against antibiotics monotherapy to understand the possible role of non-steroidal anti-inflammatory
Sandesh Gautam +7 more
doaj +1 more source
Conjugation of Steroidal and Non – Steroidal Anti- Inflammatory Drugs as Possible Mutual Prodrug
Iraqi Journal of Pharmaceutical Sciences, 2017 Prednisolone (SAID) was conjugated with ibuprofen (NSAID) through an amino acid (glycine) as a spacer arm to synthesize the following compound: Prednisolone – glycine – ibuprofen.
Muthanna D. Saud
doaj +3 more sources