Results 301 to 310 of about 221,273 (329)
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In vitro bioassays of non-steroidal phytoestrogens
The Journal of Steroid Biochemistry and Molecular Biology, 1993Some of the isoflavonoids present in human diet as well as in urine are expected to exert biologic effects as they have been reported to bind to estrogen receptors and to be estrogenic in other species. This report describes the in vitro assessment of estrogenic effects of isoflavonoids using human endometrial cells and tissue.
L, Markiewicz +3 more
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Perioperative analgesia with non-steroidal analgesics
Current Opinion in Anaesthesiology, 1998Non-steroidal anti-inflammatory drugs are widely used for perioperative analgesia as a sole analgesic after minor surgical procedures and in combination with other types of analgesics after major surgery. The development and use of new selective cyclo-oxygenase-2 inhibitors hopefully reduce the likelihood of perioperative adverse effects that may ...
P, Tarkkila, P H, Rosenberg
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1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Rogier C, Buijsman +4 more
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Non-Steroidal Anti-Inflammatory Drugs
Rheumatology, 1993Pre-clinical studies suggest that, whilst NSAIDs have similar anti-inflammatory efficacy, the potential for producing side effects varies widely between members of this class of therapeutic agents. The ways in which NSAIDs produce one of their most serious side effects, gastrointestinal damage, are outlined and consideration is given to ways of ...
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Follicular Non-Steroidal Regulators
1979Chemical messengers synthesized both within and without the ovary control follicular and oocyte maturation and ovulation. The extraovarian messengers, whose roles are better defined, are the pituitary gonadotropins-luteinizing hormone (LH) and follicle stimulating hormone (FSH).
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Non-steroidal anti-inflammatory drugs
2013Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.The consequent changes in the ...
CARBONE, CLAUDIA +2 more
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Non-steroidal interference with male fertility
Advances in Contraception, 1986This review addresses the varied history of male contraception as it applies to nonsteroidal materials. Some of the antispermatogenic agents discussed are 1) hormonally active agents; 2) luteinizing hormone-releasing hormone analogs; 3) non-hormonal agents such as nitrofurans alkylating agents thiophenes bis-diamines dinintropyrroles fluoroacetamide 1-
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Evaluating Non-steroidal Antiinflammatory Drugs
Scandinavian Journal of Rheumatology, 1988Non-steroidal antiinflammatory drugs (NSAID) are important for many reasons. First, due to their proven analgesic and antiinflammatory effects, they are important to the patients who need them for symptomatic improvement of various painful conditions (1).
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Non-Steroidal Subtype Selective Estrogens
Current Medicinal Chemistry, 2005The biological effects of estrogens are thought to be mediated by two receptors referred to as ERalpha and ERbeta. In recent years significant efforts have been devoted to the design of subtype selective ligands. These ligands are valuable tools to establish the precise biological role of each of the subtypes and to develop new generations of ...
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