Results 341 to 350 of about 225,445 (370)
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Rogier C, Buijsman +4 more
openaire +2 more sources
1999
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
openaire +1 more source
Endogenous estrogens, such as 17β-estradiol (1, Scheme 1), have long been recognized as the primary hormones involved in the development and maintenance of the female sex organs, mammary glands and other sexual characteristics. More recently, their involvement in the growth and/or function of a number of other tissues, such as the skeleton, the ...
J. A. Dodge, C. D. Jones
openaire +1 more source
European Journal of Preventive Cardiology, 2019
Excessive or inappropriate use of non-steroidal anti-inflammatory drugs can affect cardiovascular and renal function. Non-steroidal anti-inflammatory drugs, both non-selective and selective cyclooxygenase 2 inhibitors, are among the most widely used ...
A. Cabassi +6 more
semanticscholar +1 more source
Excessive or inappropriate use of non-steroidal anti-inflammatory drugs can affect cardiovascular and renal function. Non-steroidal anti-inflammatory drugs, both non-selective and selective cyclooxygenase 2 inhibitors, are among the most widely used ...
A. Cabassi +6 more
semanticscholar +1 more source
Non-Steroidal Anti-Inflammatory Drugs
Rheumatology, 1993Pre-clinical studies suggest that, whilst NSAIDs have similar anti-inflammatory efficacy, the potential for producing side effects varies widely between members of this class of therapeutic agents. The ways in which NSAIDs produce one of their most serious side effects, gastrointestinal damage, are outlined and consideration is given to ways of ...
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Follicular Non-Steroidal Regulators
1979Chemical messengers synthesized both within and without the ovary control follicular and oocyte maturation and ovulation. The extraovarian messengers, whose roles are better defined, are the pituitary gonadotropins-luteinizing hormone (LH) and follicle stimulating hormone (FSH).
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Non-steroidal anti-inflammatory drugs
2013Several DSC studies have given a better understanding of the molecular mechanisms of interaction of many non-steroidal anti-inflammatory agents (NSAIDs), such as indomethacin, ibuprofen, naproxen, nimesulide, ketoprofen and oxicam drugs with cell membranes or with simplified phospholipid-based biomembrane models.The consequent changes in the ...
CARBONE, CLAUDIA +2 more
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Evaluating Non-steroidal Antiinflammatory Drugs
Scandinavian Journal of Rheumatology, 1988Non-steroidal antiinflammatory drugs (NSAID) are important for many reasons. First, due to their proven analgesic and antiinflammatory effects, they are important to the patients who need them for symptomatic improvement of various painful conditions (1).
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Non-Steroidal Subtype Selective Estrogens
Current Medicinal Chemistry, 2005The biological effects of estrogens are thought to be mediated by two receptors referred to as ERalpha and ERbeta. In recent years significant efforts have been devoted to the design of subtype selective ligands. These ligands are valuable tools to establish the precise biological role of each of the subtypes and to develop new generations of ...
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Acute kidney injury associated with non-steroidal anti-inflammatory drugs.
European journal of internal medicine, 2022N. Klomjit, P. Ungprasert
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