Results 251 to 260 of about 152,017 (383)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Current Status of Non-Steroid Anti-inflammatory Topical Agents in Fukuoka Prefecture

, 1984
Keiko Nishitani, Masaaki Takeishi
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

Perioperative nonsteroidal anti-inflammatory drugs and the risk for anastomotic leakage in patients undergoing major gastrointestinal surgery: a retrospective cohort study. [PDF]

BMC Anesthesiol
Zhang H, Zhao F, Zhang T, Shi L, Han S, Lv X, Li H, Lou J, Cao J, Mi W, Liu Y.   +10 more
europepmc   +1 more source

Comparative Outcomes of Endoscopic Treatment for Symptomatic and Asymptomatic Common Bile Duct Stones in the Elderly: A Propensity Score‐Based Cohort Analysis

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Various guidelines recommend endoscopic stone removal for asymptomatic common bile duct stones (CBDS); however, previous studies have indicated that asymptomatic CBDS is associated with a higher incidence of post‐ERCP pancreatitis (PEP).
Kota Shimojo, Akinori Maruta, Keisuke Iwata, Yuhei Iwasa, Mitsuru Okuno, Kensaku Yoshida, Shinya Uemura, Tsuyoshi Mukai, Takuji Iwashita, Masahito Shimizu   +9 more
wiley   +1 more source

The antitumor potential of <i>Polygonatum</i> spp.: a narrative review of traditional uses, bioactive metabolites, and multi-targeted mechanisms. [PDF]

Front Pharmacol
Zhu M, Chen G, Li J, Yi C, Yuan Y, Liu W, Zhang X.   +6 more
europepmc   +1 more source

Organ selective inhibition of prostaglandin generation invivo by a non-steroidal anti-inflammatory agent, AD-1590, in rats

, 1986
H Nakamura, Satoru Motoyoshi, Yasuhiro Seto, Toshiaki Kadokawa, Masanao Shimizu   +4 more
openalex   +1 more source

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS). [PDF]

Reprod Biol Endocrinol
Shi Z, Li Z, Li Y, Yang F.
europepmc   +1 more source

Adequate vitamin D is associated with favorable disease outcome in children with inflammatory bowel disease receiving anti‐tumor necrosis factor alpha therapy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Deficiency of serum 25‐hydroxyvitamin D [25(OH)D] was associated with decreased short‐term response to anti‐tumor necrosis factor‐alpha (TNF‐α) agents in adults with inflammatory bowel disease (IBD). The aim of this study was to evaluate the association between serum 25(OH)D levels and the outcome of children with IBD undergoing ...
Adi Anafy, Yaara Manor, Maayan Shemer, Reut Doyev, Eytan Damari, Shlomi Cohen, Anat Yerushalmy‐Feler   +6 more
wiley   +1 more source