Results 21 to 30 of about 107,188 (298)

Fused Triazole-Azepine Hybrids as Potential Non-Steroidal Antiinflammatory Agents

Scientia Pharmaceutica, 2023
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the oldest and most widely used groups of drugs nowadays. However, the problem of searching for and creating new NSAIDs remains open, primarily due to the risks owing to their short- and long-term
Sergii Demchenko, Roman Lesyk, Oleh Yadlovskyi, Serhii Holota, Sergii Yarmoluk, Sergii Tsyhankov, Anatolii Demchenko   +6 more
doaj   +1 more source

A gastroenterologist and arheumatologist answer the questions on the use ofnon-steroidal anti-inflammatory drugs raised by primary care physicians

Pediatria i Medycyna Rodzinna, 2016
Non-steroidal anti-inflammatory drugs are drugs of choice for chronic pain, which is most common in chronic conditions, rheumatism in particular. According to  current recommendations, these medications should be used continuously or intermittently ...
Przemysław Dyrla, Jerzy Gil, Brygida Kwiatkowska   +2 more
doaj   +1 more source

Potential Strategies in the Prevention of Nonsteroidal Anti-inflammatory Drugs-Associated Adverse Effects in the Lower Gastrointestinal Tract

Gut and Liver, 2020
With the increasing use of nonsteroidal anti-inflammatory drugs (NSAIDs), the incidence of lower gastrointestinal (GI) complications is expected to increase.
Chuan-Guo Guo, Wai K. Leung
doaj   +1 more source

Risk Factors for the Presence of Symptoms in Peptic Ulcer Disease [PDF]

Clinical Endoscopy, 2017
Background/Aims Peptic ulcer disease (PUD) is a common condition, but is difficult to detect in asymptomatic individuals. We aimed to investigate the prevalence of symptomatic and asymptomatic PUD during screening endoscopy and to identify risk factors ...
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim   +5 more
doaj   +1 more source

Encouraging physician appropriate prescribing of non-steroidal anti-inflammatory therapies: protocol of a randomized controlled trial [ISRCTN43532635]

BMC Health Services Research, 2004
Background Traditional non-steroidal anti-inflammatory drugs (NSAIDs) are a widely used class of therapy in the treatment of chronic pain and inflammation.
Metge Colleen, Manness Lori-Jean, Kvern Brent, Katz Alan, Doupe Malcolm, Thomson Glen TD, Morrison Laura, Rother Kat   +7 more
doaj   +1 more source

Tauroursodeoxycholic Acid Inhibits Nuclear Factor Kappa B Signaling in Gastric Epithelial Cells and Ameliorates Gastric Mucosal Damage in Mice

The Korean Journal of Gastroenterology, 2022
Background/Aims: Previous studies have reported the protective effects of tauroursodeoxycholic acid (TUDCA) on gastric epithelial cells in some animal models, but the precise mechanisms are unclear.
Su Hwan Kim, Ji Won Kim, Seong-Joon Koh, Sang Gyun Kim, Jeong Mo Bae, Jung Ho Kim, Jeong Hwan Park, Kee Don Choi, Hyoun Woo Kang, Byeong Gwan Kim , Kook Lae Lee   +10 more
doaj   +1 more source

Synthesis and anti-inflammatory evaluation of novel thiadiazol derivatives of Mefenamic acid

Bulletin of the Chemical Society of Ethiopia, 2017
In the search for new potential non-steroidal anti-inflammatory agents, some novel Mefenamic acid derivatives were synthesized and confirmed by spectroscopic data.
A. Ahmadi
doaj   +1 more source

Nonsteroidal Anti-inflammatory Drug and Aspirin-induced Peptic Ulcer Disease

The Korean Journal of Gastroenterology, 2016
Despite decreasing Helicobacter pylori prevalence, the prevalence of peptic ulcer disease is increasing in the aged population, mainly due to increasing use of NSAIDs to manage pain and inflammation.
Young Kwang Shim, Nayoung Kim
doaj   +1 more source

Refractory Peptic Ulcer Disease [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2019
The eradication of Helicobacter pylori and the widespread use of effective antisecretory therapies, including proton pump inhibitors, have improved the management of peptic ulcer disease. However, in some patients, peptic ulcer disease is refractory to 8
Hyun Lim
doaj   +1 more source

Safety and tolerability of nsaids: focus on aceclofenac

Медицинский совет, 2019
The article discusses the main problems of safety of non-steroidal anti-inflammatory agents (NSAIDs). The results of randomized clinical studies, pharmacoepidemiological studies and meta-analyses suggesting higher safety of aceclofenac compared to ...
E. A. Ushkalova, S. K. Zyryanov, K. E. Zalolochina   +2 more
doaj   +1 more source