Results 71 to 80 of about 13,491,336 (252)
Advanced Science, EarlyView.GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han +16 more
wiley +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Effectiveness of anti-inflammatory premedication on inferior alveolar nerve block success in acute irreversible pulpitis: a systematic review [PDF]
Exploration of MedicineBackground: Irreversible pulpitis is commonly associated with reduced success of inferior alveolar nerve block (IANB) during root canal treatment, often leading to inadequate intraoperative pain control.
Alessio Danilo Inchingolo +11 more
doaj +1 more source
Translational Neuroscience, 2023 Headache attributed to craniotomy is an underestimated and under-treated condition. Previous studies confirmed the efficacy of preemptive analgesia with non-steroidal anti-inflammatory agents.
Simon Éva +8 more
doaj +1 more source
The Use of Non-steroidal Anti-inflammatory Drugs, and Analgesics, Antipyretics and Anaesthetics at Ohu University Dental Hospital during the Years 2000 through 2003 [PDF]
, 2005 P(論文)We studied the type, quantity and circumstances of non-steroidal anti-inflammatory drugs, and analgesics, antipyretics and anaesthetics medications at the Hospital of the Ohu University School of Dentistry during the years 2000 through 2003.
浜田, 節男 +11 more
core
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Musculoskeletal pain: determination of clinical phenotypes and the rational treatment approach
Alʹmanah Kliničeskoj Mediciny, 2019 Personalized treatment is one of the basic principles of modern medicine. When administering a treatment, one should consider individual patient characteristics, comorbidities and, what is most important, the prevailing symptoms, as well as the clinical ...
A. E. Karateev
doaj +1 more source
Non-steroidal anti-inflammatory drugs types.
, 2019 Non-steroidal anti-inflammatory drugs types.
Alberto Villarejo-Galende (7392335) +4 more
core +1 more source
Advanced Science, EarlyView.HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun +12 more
wiley +1 more source
Topical diclofenac: Clinical effectiveness and current uses in osteoarthritis of the knee and soft tissue injuries [PDF]
, 2008 Background: Diclofenac is a commonly used non-steroidal anti-inflammatory drug (NSAID) for symptom control in osteoarthritis (OA) of the knee and soft tissue injuries.
Banning, M
core +1 more source