Results 151 to 160 of about 13,032,507 (249)

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.

Erbil Dental Journal
Background and objectives: The steroidal and Non-Steroidal Anti-Inflammatory drugs (NSAIDs) are widely used classes of medications for their anti-Inflammatory and analgesic effects and are associated with the risk of many oral side effects and which ...
Shayma Ghazi, Khalid Yasin Rasul, Aras Khidhir Hamad, Aso Abdulkhaliq Khidhir, Lozan Khalil Ahmed   +4 more
doaj  

Is there a link between non-steroidal anti-inflammatory drugs and cardiovascular risk in patients with inflammatory arthritis? [PDF]

Atheroscler Plus
Zingler G, Baerwald C.
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Efficacy of intranasal non-steroidal anti-inflammatory drugs on pain responses in castrated and tail-docked piglets. [PDF]

Porcine Health Manag
de Melo CAF, Alves LKS, Pairis-Garcia MD, Ferreira JB, Parker TB, Merenda VR, Messenger KM, Trindade PHE.   +7 more
europepmc   +1 more source

Impact of cumulative glucocorticoid exposure on vancomycin clearance in hospitalized children: A retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Prior glucocorticoid exposure is associated with modestly increased vancomycin clearance in hospitalized children, partly mediated by renal function and inflammation and may contribute to subtherapeutic early drug exposure. Abstract Introduction Augmented renal clearance (ARC) can lead to subtherapeutic vancomycin exposure in children.
Kouki Tomari, Ruud H. J. Verstegen, Cintia Cruz, Erin Chung, Aleena Azim, Shinya Ito, Tamorah R. Lewis   +6 more
wiley   +1 more source

Erdosteine Provides Effective Analgesia in Inflammatory Pain Without Impairing Pain Resolution: A Preclinical Comparison With Non-Steroidal Anti-Inflammatory Drugs. [PDF]

Eur J Pain
Vasconcelos Lima L, Karaky M, Yu G, Allegri M, Marchesi N, Govoni S, Page C, Diatchenko L.   +7 more
europepmc   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Detecting Adverse Events Following Acute Care Encounters among Veterans Prescribed Non-Steroidal Anti-Inflammatory Drugs. [PDF]

J Am Coll Emerg Physicians Open
Hackstadt AJ, Perkins AM, Wrenn JO, Reese TJ, Rubenstein MD, Winter R, Dorn CA, Martino MR, Han JH, Ward MJ, Matheny ME.   +10 more
europepmc   +1 more source

Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing

British Journal of Clinical Pharmacology, EarlyView.
The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët, Steven R. Kraaijeveld, Erik M. Donker, Milan C. Richir, Caroline T. A. Moermond, Amy Booth, SanYuMay Tun, Thijs H. Oude Munnink, Patricia M. L. A. van den Bemt, Lorena Dima, Ben J. A. Janssen, Mathilde Jalving, Tomás Mauro van Emden, Fabrizio de Ponti, Robert Likic, João Costa, Marc Labriffe, Charlotte L. Bekker, Carlotta Lunghi, Elisabetta Poluzzi, Michiel A. van Agtmael, Yolande Voskes, Jelle Tichelaar   +22 more
wiley   +1 more source