Results 81 to 90 of about 13,032,507 (249)

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
Juhász Viktor, István Koncz, Biliczki, Péter, Kristóf Attila, Virág, László, Viktor Juhász, Papp Gyula, Papp Julius Gy, Szél Tamás, Varró András, Kristóf, Attila, Norbert Jost, András Varró, Attila Kristóf, Baczkó István, Virág László, Kohajda, Zsófia, László Virág, Husti, Zoltán, Juhász, Viktor, Zsófia Kohajda, Baczkó, István, Kohajda Zsófia, Biliczki Péter, Julius Gy Papp, Jost Norbert László, Jost, Norbert, Husti Zoltán, Varró, András, Tamás Szél, Jost Norbert, Koncz István, Péter Biliczki, Szél, Tamás, István Baczkó, Papp, Gyula, Zoltán Husti   +36 more
core   +2 more sources

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

ANTI-INFLAMMATORY THERAPY BY FENSPIRIDE IN PATIENTS WITH PATHOLOGY OF UPPER AND LOWER RESPIRATORY TRACTS

Медицинский совет, 2016
In the treatment of patients with diseases of the upper and lower respiratory tract it is necessary to conduct anti-inflammatory therapy. Up to the present time two groups of anti-inflammatory drugs were used: corticosteroids (CSs) and non-steroidal ...
O. A. TSVETKOVA
doaj   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Patient educational materials on non-steroidal anti-inflammatory drugs

Proceedings of Singapore Healthcare
Introduction Effectiveness of Patient Education Materials (PEMs) on NSAIDs is subjected to whether the patient is able to read and comprehend the information provided.
Bandy Qiuling Goh, Cynthia Ciwei Lim, Sheila Kai Xuan Toh, Puay Hoon Lee, Ngiap Chuan Tan   +4 more
doaj   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Non-steroidal Anti-inflammatory Drug Prescriptions in Living Kidney Donors: A Retrospective Cohort Study

Canadian Journal of Kidney Health and Disease
Background: Current guidelines recommend that living kidney donors should avoid non-steroidal anti-inflammatory drugs due to their potential nephrotoxic effects. It is unclear if physicians are adhering to this recommendation.
Mikayla I. Laube, Robert R. Quinn, Pietro Ravani, Krista L. Lentine, Alix Clarke, Rachel Jeong, Jason Bau, Ngan N. Lam   +7 more
doaj   +1 more source

Impaired Chaperone‐Mediated Autophagy Accelerates Intervertebral Disc Degeneration by Inducing MIDN Accumulation to Target TSC2 for Proteasomal Degradation

Advanced Science, EarlyView.
This graphical abstract illustrates how chaperone‐mediated autophagy (CMA) regulates intervertebral disc degeneration (IDD). Under normal homeostasis (B), CMA degrades cytoplasmic Midnolin (MIDN) to maintain proteostasis. Under inflammatory stress (A), impaired CMA leads to cytoplasmic MIDN accumulation.
Xianglong Chen, Haiyang Gao, Wang Wu, Pengzhi Shi, Yuhang Chen, Anran Zhang, Zhangrong Cheng, Wenbo Wu, Zimu Yu, Yukun Zhang   +9 more
wiley   +1 more source

The role of transcutaneous electrical nerve stimulation for menstrual pain relief: A randomized control trial

Women's Health
Background: Abdominal pain due to menses (primary dysmenorrhea) is an extremely pervasive and debilitating symptom affecting up to 90% of menstruating individuals. Objective: The objective of this randomized control trial was to investigate the effect of
Bailey McLagan, Joshua Dexheimer, Nicole Strock, Shayna Goldstein, Stephanie Guzman, David Erceg, E Todd Schroeder   +6 more
doaj   +1 more source