Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo. [PDF]
, 2014 Spores of some species of the strictly anaerobic bacteria Clostridium naturally target and partially lyse the hypoxic cores of tumors, which tend to be refractory to conventional therapies. The anti-tumor effect can be augmented by engineering strains to
Dubois, L +10 more
core +7 more sources
Tomato resistance to Alternaria stem canker: localization in host genotypes and functional expression compared to non-host resistance [PDF]
, 1989 The Alternaria stem canker resistance locus (Asc-locus), involved in resistance to the fungal pathogen Alternaria alternata f. sp. lycopersici and in insensitivity to host-specific toxins (AAL-toxins) produced by the pathogen, was genetically mapped on ...
Griend, E.G. van de, +4 more
core +2 more sources
Breaking through the glioblastoma micro-environment via extracellular vesicles [PDF]
, 2020 Glioblastoma (GBM) is the most common and most aggressive brain tumour. Prognosis remains poor, despite the combined treatment of radio- and chemotherapy following surgical removal.
Giamas, Georgios +2 more
core +1 more source
Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae. [PDF]
, 2014 BackgroundSusceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses.
Anishchenko, Michael +5 more
core +3 more sources
Physiological and Molecular Characterization of Hydroxyphenylpyruvate Dioxygenase (HPPD)-inhibitor Resistance in Palmer Amaranth (Amaranthus palmeri S. Wats.) [PDF]
, 2017 Citation: Nakka, S., Godar, A. S., Wani, P. S., Thompson, C. R., Peterson, D. E., Roelofs, J., & Jugulam, M. (2017). Physiological and Molecular Characterization of Hydroxyphenylpyruvate Dioxygenase (HPPD)-inhibitor Resistance in Palmer Amaranth ...
Godar, A. S. +6 more
core +1 more source
Journal of Plant Protection Research, 2017 Three populations of silky bent grass (Apera spica-venti L.) were tested – one that is susceptible and two that are resistant to sulfonylureas. This study assessed the efficacy of control by different herbicides in a pot experiment and estimated the ...
Stankiewicz-Kosyl Marta +3 more
doaj +1 more source
Role of a novel I1781T mutation and other mechanisms in conferring resistance to acetyl-CoA carboxylase inhibiting herbicides in a black-grass population. [PDF]
PLoS ONE, 2013 BACKGROUND: Knowledge of the mechanisms of herbicide resistance is important for designing long term sustainable weed management strategies. Here, we have used an integrated biology and molecular approach to investigate the mechanisms of resistance to ...
Shiv Shankhar Kaundun +3 more
doaj +1 more source
Non-target-site glyphosate resistance in Echinochloa colona from Western Australia
Crop Protection, 2018 Abstract An Echinochloa colona population from Western Australia has evolved resistance to glyphosate. This current study investigates the physiological, molecular and biochemical basis of glyphosate resistance in this population. To minimise genetic differences the susceptible (S) and resistance (R) phenotypes were isolated from within this ...
Sou Sheng Goh +5 more
openaire +2 more sources
Plants, 2019 Intentional use of low dosage of herbicides has been considered the cause of non-target resistance in weeds. However, herbicide drift could be a source of low dosage that could be detected by weeds and change their metabolism.
J António Tafoya-Razo +3 more
doaj +1 more source
Julius-Kühn-Archiv, 2014 The repetitive use of herbicides of a given mode of action as primary tools to control weeds in simplified cropping systems has led to the development of resistant populations.
Herrmann, Johannes +5 more
doaj +1 more source