Results 51 to 60 of about 1,263,679 (284)

Weed resistance diagnostic technologies to detect herbicide resistance in cerealgrowing areas. A review

open access: yesJulius-Kühn-Archiv, 2012
Cereals are major crops used for food and feed. By 2050, the world population is expected to be close to 10 billion requiring a doubling of the food production from a fixed area of arable land.
Beffa, Roland   +6 more
doaj   +1 more source

New Clox Systems for rapid and efficient gene disruption in Candida albicans [PDF]

open access: yes, 2014
Acknowledgements: We are grateful to Janet Quinn, Lila Kastora, Joanna Potrykus, Michelle Leach, and others for sharing their experiences with the Clox cassettes.
Ballou, Elizabeth R   +6 more
core   +7 more sources

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Status and development of ACCase and ALS inhibitor resistant black-grass (Alopecurus myosuroides Huds.) in neighboring fields in Germany

open access: yesJulius-Kühn-Archiv, 2012
Neighboring fields in three local areas of southern Germany have been investigated for the infestation level and herbicide resistance structure of black-grass (Alopecurus myosuroides Huds.).
Hess, Martin   +5 more
doaj   +1 more source

"Non-Target-Site" resistance mechanisms of "Papaver rhoeas" L. biotypes with multiple resistance [PDF]

open access: yes, 2015
Hasta el momento en España no se han desarrollado estudios a fin de evaluar los mecanismos de resistencia “Non-Target-Site” en “Papaver rhoeas”. Tras constatar la resistencia múltiple de los biotipos empleados en este ensayo, los resultados de absorción ...
Menéndez, J.   +3 more
core  

Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage [PDF]

open access: yes, 2008
Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood.
Binaschi   +34 more
core   +1 more source

Genetic Mechanism of Non-Targeted-Site Resistance to Diquat in Spirodela polyrhiza

open access: yesPlants
Understanding non-target-site resistance (NTSR) to herbicides represents a pressing challenge as NTSR is widespread in many weeds. Using giant duckweed (Spirodela polyrhiza) as a model, we systematically investigated genetic and molecular mechanisms of diquat resistance, which can only be achieved via NTSR.
Martin Höfer   +4 more
openaire   +3 more sources

Target-site and non-target-site resistance mechanisms confer multiple resistance to glyphosate and 2,4-D in Carduus acanthoides

open access: yesPesticide Biochemistry and Physiology, 2023
Carduus acanthoides L. is mainly a range-land weed, but in the 2010s has begun to invade GM crop production systems in Córdoba (Argentina), where glyphosate and 2,4-D have been commonly applied. In 2020, C. acanthoides was found with multiple resistance to these two herbicides. In this study, the mechanisms that confer multiple resistance to glyphosate
Palma-Bautista, Candelario   +6 more
openaire   +5 more sources

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta [PDF]

open access: yes, 2017
Preventive chemotherapy has long been practiced against nematode parasites of livestock, leading to widespread drug resistance, and is increasingly being adopted for eradication of human parasitic nematodes even though it is similarly likely to lead to ...
Bisset, Stewart A   +6 more
core   +4 more sources

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