Results 81 to 90 of about 1,263,679 (284)

Broad resistance to ACCase inhibiting herbicides in a ryegrass population is due only to a cysteine to arginine mutation in the target enzyme. [PDF]

PLoS ONE, 2012
BACKGROUND: The design of sustainable weed management strategies requires a good understanding of the mechanisms by which weeds evolve resistance to herbicides. Here we have conducted a study on the mechanism of resistance to ACCase inhibiting herbicides
Shiv Shankhar Kaundun, Sarah-Jane Hutchings, Richard Paul Dale, Eddie McIndoe   +3 more
doaj   +1 more source

Glyphosate resistance in annual ryegrass (Lolium rigidum Gaud.) with multiple resistance mechanisms. [PDF]

, 2010
Glyphosate (N-(phosphonomethyl)glycine) is a post-emergent, systemic and non-selective herbicide for the control of annual and perennial weeds. This herbicide has very low toxicity to the mammals.
Bostamam, Yazid
core   +1 more source

Perspectives on non-target site mechanisms of herbicide resistance in weedy plant species using evolutionary physiology [PDF]

AoB PLANTS, 2017
Evolutionary physiology merges the disciplines of evolution and physiology, and it is a research approach that has not received much attention for studying the development of herbicide resistance. This paper makes a case for using evolutionary physiology more frequently when studying herbicide resistance, and illustrates this using three areas where ...
Ghanizadeh, Hossein, Harrington, Kerry C
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Molecular dynamics simulations and docking of non-nucleoside reverse transcriptase inhibitors (NNRTIs): a possible approach to personalized HIV treatment : from 7th German Conference on Chemoinformatics: 25 CIC-Workshop Goslar, Germany, 6 - 8 November 2011 [PDF]

, 2012
The human immunodeficiency virus (HIV) is currently ranked sixth in the worldwide causes of death [1]. One treatment approach is to inhibit reverse transcriptase (RT), an enzyme essential for reverse transcription of viral RNA into DNA before integration
Bender, Andreas, Bond, Peter J., Korb, Oliver, Mäntele, Werner, Roessler, Florian D.   +4 more
core  

Target-site mutations (AChE and kdr), and PSMO activity in codling moth (Cydia pomonella (L.) (Lepidoptera: Tortricidae)) populations from Spain [PDF]

, 2018
Codling moth, Cydia pomonella (L.) is a key pest of global importance that affects apple fruit production and whose populations have developed resistance to insecticides in many apple production areas.
Avilla Hernández, Jesús, Bosch Serra, Dolors, Musleh, Selim, Rodríguez García, Marcela   +3 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nucleotide Diversity at Site 106 of EPSPS in Lolium perenne L. ssp. multiflorum from California Indicates Multiple Evolutionary Origins of Herbicide Resistance

Frontiers in Plant Science, 2017
The repeated evolution of herbicide resistance in weeds is an ongoing problem in agricultural regions across the world, and presents a unique system in which to study the origins and spread of adaptive traits across heterogeneous landscapes.
Elizabeth Karn, Marie Jasieniuk
doaj   +1 more source

Herbicide mixtures at high doses slow the evolution of resistance in experimentally evolving populations of Chlamydomonas reinhardtii [PDF]

, 2013
The widespread evolution of resistance to herbicides is a pressing issue in global agriculture. Evolutionary principles and practices are key to the management of this threat to global food security.
Colegrave, Nick, Lagator, Mato, Mead, A. (Andrew), Neve, Paul, Vogwill, Tom   +4 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source