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High-resolution mass spectrometry (HRMS) is widely used for the drug screening of biological samples in clinical and forensic laboratories. With the continuous addition of new psychoactive substances (NPS), keeping such methods updated is challenging ...
Christian Brinch Mollerup +2 more
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International audienceComplementarity of targeted and nontargeted screening of organohalogens is studied. • Targeted quantification of legacy and novel BFRs, CPs and PCBs (n > 80).
Stéphane Bayen +2 more
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Data acquisition methods for non-targeted screening in environmental analysis
TrAC - Trends in Analytical Chemistry, 2023Yujue Yang, Lili Yang, Minghui Zheng
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Targeted and non-targeted screening of flame retardants in rural and urban honey
Chemosphere, 2023Flame retardants (FRs) are often added to commercial products to achieve flammability resistance, but they are not chemically bonded to the materials, so, they can be easily released into the environment during the production and disposal processes.
Gabriel Leung +5 more
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Non-targeted Screening in Environmental Monitoring Programs
2019Contaminant monitoring programs have been tasked with understanding the fate and transport of toxic chemicals in the environment. Mass spectrometry based methods have traditionally been developed to maximize sensitivity and accuracy of a select set of target compounds. As mass spectrometry methods have advanced, so has the breadth of questions proposed
Bernard S, Crimmins, Thomas M, Holsen
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Monitoring veterinary drug residues in food is one key link to ensuring food safety. In recent years, non-targeted screening technology based on liquid chromatography-high resolution mass spectrometry (LC-HRMS) has attracted widespread attention. However,
Anastasios Koidis +2 more
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How Unbiased is Non-Targeted Metabolomics and is Targeted Pathway Screening the Solution?
Current Pharmaceutical Biotechnology, 2011Metabolomics is only truly unbiased if the whole metabolome is captured. Current metabolomics technologies capture only a part of the metabolome and therefore produce inherently biased results. Important factors that introduce such bias into a metabolomic analysis may include but are not limited to, timing of sample collection, the sample collection ...
Uwe, Christians +3 more
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A method for rapid, non-targeted screening for environmental contaminants in household dust
Journal of Chromatography A, 2010Household dust can be a major source of human exposure to environmental contaminants such as polybrominated diphenyl ethers, pesticides, and other compounds. This work shows a screening technique that may be used to identify components in an environmental sample as xenobiotics based on mass spectral characteristics of classes of compounds that may be ...
Donald C, Hilton +2 more
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