Results 241 to 250 of about 592,569 (295)

National survey of urologists' views on prostate cancer screening in the United Kingdom. [PDF]

BJUI Compass
Mayor N, Rawlins F, Cullen E, Sonigra-Patel V, Gabe R, Ahmed HU.   +5 more
europepmc   +1 more source

Spatial non-targeted screening and machine learning-based risk assessment of organic pollutants in honey from Bhakkar District, Pakistan

M. I. Baloch, Abrar Hussain, Syed Naqvi, Khurram Shahzad, Khaled Chawraba, Tahir Mehmood, Azhar Mahmood, Sang Hyun Park   +7 more
openalex   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

LDCT screening for lung cancer in East Asian never-smokers: balancing benefits and overdiagnosis-related harms. [PDF]

Lancet Reg Health West Pac
Xu X, Chen H, Xu W.
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Stratified obstetric management for heterogeneous rare diseases: a precision medicine framework based on four genetic archetypes. [PDF]

Front Med (Lausanne)
Lv S, Yang H, Cui Y, Yang H.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A comprehensive review of gastrointestinal cancers: epidemiology, risk factors, diagnosis, and therapeutic strategies. [PDF]

Am J Transl Res
Yang Z, Lin F, Shen H, Jamil M, Wang X.
europepmc   +1 more source

Pollution by Polar Pesticides and Pharmaceuticals and Risk Assessment in Surface Water Bodies Along the French Mediterranean Coast: Complementarity of Target and Non-Target Screenings

Nicolas Martin, Geoffroy Duporté, Étienne Lemaire, André Sauvetre, Marine Bertrand, David Rosain, Elena Góméz, Émilie Farcy   +7 more
openalex   +1 more source

Analysis and Risks of Emerging Contaminants and Microplastics in Natural and Treated Waters and Human Health: A Critical Review. [PDF]

J Xenobiot
Mallek M, Barceló D.
europepmc   +1 more source