Results 1 to 10 of about 530,809 (300)

Secondary ion mass spectrometry imaging of Dictyostelium discoideum aggregation streams. [PDF]

PLoS ONE, 2014
High resolution imaging mass spectrometry could become a valuable tool for cell and developmental biology, but both, high spatial and mass spectral resolution are needed to enable this.
John Daniel DeBord, Donald F Smith, Christopher R Anderton, Ron M A Heeren, Ljiljana Paša-Tolić, Richard H Gomer, Francisco A Fernandez-Lima   +6 more
doaj   +11 more sources

Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry. [PDF]

PLoS ONE, 2013
Metabolomics can provide exciting insights into organismal function, but most work on simple models has focussed on the whole organism metabolome, so missing the contributions of individual tissues.
Venkateswara R Chintapalli, Mohammed Al Bratty, Dominika Korzekwa, David G Watson, Julian A T Dow   +4 more
doaj   +6 more sources

Proteogenomic analysis of Cyprinid herpesvirus 2 using high-resolution mass spectrometry [PDF]

Journal of Virology
Cyprinid herpesvirus 2 (CyHV-2) is the main pathogen responsible for the development of herpesviral hematopoietic necrosis disease (HVHND) in crucian carp (Carassius auratus). The CyHV-2 genome encodes approximately 150 genes that are expressed in a well-
Chen Xu, Fangxing Yu, Mingyang Xue, Zhenyu Huang, Nan Jiang, Yiqun Li, Yan Meng, Wenzhi Liu, Ya Zheng, Yuding Fan, Yong Zhou   +10 more
doaj   +2 more sources

iDOM: Statistical analysis of dissolved organic matter characterized by high‐resolution mass spectrometry [PDF]

mLife
Dissolved organic matter (DOM) contains thousands of molecules and is key for biogeochemical cycles in aquatic and terrestrial ecosystems by interacting with microbes.
Fanfan Meng, Ang Hu, Kyoung‐Soon Jang, Jianjun Wang   +3 more
doaj   +2 more sources

The Development of New Methodology for Determination of Vincristine (VCR) in Human Serum Using LC-MS/MS-Based Method for Medical Diagnostics

Molecules, 2022
In this article, we have presented the development and validation of a rapid and sensitive reversed-phase liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the determination of vincristine (VCR) in patient serum samples ...
Kamil Jurowski, Łukasz Paprotny, Marcin Zakrzewski, Dorota Wianowska, Joanna Kasprzyk-Pochopień, Małgorzata Herman, Katarzyna Madej, Wojciech Piekoszewski, Tomasz Kubrak   +8 more
doaj   +1 more source

Effects of excessive alcohol drinking on nicotine biotransformation in rats

Scientific Reports, 2022
Alcohol and nicotine (tobacco smoke) are often used together, and taking both addictive substances is associated with an increased risk of certain diseases. It is extremely important to understand the pharmacodynamic and pharmacokinetic mechanisms of the
Joanna Kasprzyk, Wojciech Piekoszewski, Artur Tezyk, Maksymilian Kulza, Ewa Florek   +4 more
doaj   +1 more source

Evaluation of the Protective and Regenerative Properties of Commercially Available Artichoke Leaf Powder Extract on Plasma and Liver Oxidative Stress Parameters

Antioxidants, 2023
Hepatocellular damage by the harmful effects of xenobiotics, which increase the production of free radicals, is a widespread phenomenon. The extract from the leaves of Cynara scolymus L.
Ewa Florek, Marta Szukalska, Katarzyna Markiewicz, Izabela Miechowicz, Justyna Gornowicz-Porowska, Anna Jelińska, Joanna Kasprzyk-Pochopień, Joanna Nawrot, Agnieszka Sobczak, Małgorzata Horoszkiewicz, Wojciech Piekoszewski, Gerard Nowak   +11 more
doaj   +1 more source

Proteomic profiling of Serratia marcescens by high-resolution mass spectrometry [PDF]

BioImpacts, 2020
Introduction: Serratia marcescens, an opportunistic human pathogen, is reported as an important cause of nosocomial infection and outbreaks. Although the genome of S.
Bhavya Somalapura Gangadharappa, Sharath Rajashekarappa, Gajanan Sathe   +2 more
doaj   +1 more source

Acyl-Lipid Δ⁶-Desaturase May Act as a First FAD in Cyanobacteria

Biomolecules, 2022
Fatty acid desaturases (FADs) play important roles in various metabolic and adaptive pathways in all living organisms. They represent a superfamily of oxygenases that introduce double bonds into the acyl chains of fatty acids (FAs).
Alexander Y. Starikov, Roman A. Sidorov, Sergei V. Goriainov, Dmitry A. Los   +3 more
doaj   +1 more source

Advances in Ultra-High-Resolution Mass Spectrometry for Pharmaceutical Analysis

Molecules, 2023
Pharmaceutical analysis refers to an area of analytical chemistry that deals with active compounds either by themselves (drug substance) or when formulated with excipients (drug product).
Estelle Deschamps, Valentina Calabrese, Isabelle Schmitz, Marie Hubert-Roux, Denis Castagnos, Carlos Afonso   +5 more
doaj   +1 more source