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In this article, we have presented the development and validation of a rapid and sensitive reversed-phase liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the determination of vincristine (VCR) in patient serum samples ...
Kamil Jurowski +8 more
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Effects of excessive alcohol drinking on nicotine biotransformation in rats
Alcohol and nicotine (tobacco smoke) are often used together, and taking both addictive substances is associated with an increased risk of certain diseases. It is extremely important to understand the pharmacodynamic and pharmacokinetic mechanisms of the
Joanna Kasprzyk +4 more
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Proteomic profiling of Serratia marcescens by high-resolution mass spectrometry [PDF]
Introduction: Serratia marcescens, an opportunistic human pathogen, is reported as an important cause of nosocomial infection and outbreaks. Although the genome of S.
Bhavya Somalapura Gangadharappa +2 more
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Hepatocellular damage by the harmful effects of xenobiotics, which increase the production of free radicals, is a widespread phenomenon. The extract from the leaves of Cynara scolymus L.
Ewa Florek +11 more
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Acyl-Lipid Δ6-Desaturase May Act as a First FAD in Cyanobacteria
Fatty acid desaturases (FADs) play important roles in various metabolic and adaptive pathways in all living organisms. They represent a superfamily of oxygenases that introduce double bonds into the acyl chains of fatty acids (FAs).
Alexander Y. Starikov +3 more
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Advances in Ultra-High-Resolution Mass Spectrometry for Pharmaceutical Analysis
Pharmaceutical analysis refers to an area of analytical chemistry that deals with active compounds either by themselves (drug substance) or when formulated with excipients (drug product).
Estelle Deschamps +5 more
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Cottonseed hull is a livestock feed with large daily consumption. If pesticide residues exceed the standard, it is easy for them to be introduced into the human body through the food chain, with potential harm to consumer health.
Kaixuan Tong +8 more
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Fast and Accurate Identification of Candida auris by High Resolution Mass Spectrometry
The emerging pathogen Candida auris has been associated with nosocomial outbreaks on six continents. Genetic analysis indicates simultaneous and independent emergence of separate clades of the species in different geographical locations.
Azadeh Jamalian +5 more
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Proteomic Analysis of Cardiac Adaptation to Exercise by High Resolution Mass Spectrometry
Regular exercise has many health benefits, among which is a significant reduction of cardiovascular risk. Although many beneficial effects of exercise are well described, the exact mechanisms by which exercise confers cardiovascular benefits are yet to ...
Afnan Saleh Al-Menhali +7 more
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Impurity Profiling of Dinotefuran by High Resolution Mass Spectrometry and SIRIUS Tool
Dinotefuran (DNT) is a neonicotinoid insecticide widely used in pest control. Identification of structurally related impurities is indispensable during material purification and pesticide registration and certified reference material development, and ...
Xianjiang Li +5 more
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