Results 11 to 20 of about 255,468 (310)
Molecules, 2022 In this article, we have presented the development and validation of a rapid and sensitive reversed-phase liquid chromatography with tandem mass spectrometry (LC-MS/MS) method for the determination of vincristine (VCR) in patient serum samples ...
Kamil Jurowski +8 more
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Effects of excessive alcohol drinking on nicotine biotransformation in rats
Scientific Reports, 2022 Alcohol and nicotine (tobacco smoke) are often used together, and taking both addictive substances is associated with an increased risk of certain diseases. It is extremely important to understand the pharmacodynamic and pharmacokinetic mechanisms of the
Joanna Kasprzyk +4 more
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Antioxidants, 2023 Hepatocellular damage by the harmful effects of xenobiotics, which increase the production of free radicals, is a widespread phenomenon. The extract from the leaves of Cynara scolymus L.
Ewa Florek +11 more
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Proteomic profiling of Serratia marcescens by high-resolution mass spectrometry [PDF]
BioImpacts, 2020 Introduction: Serratia marcescens, an opportunistic human pathogen, is reported as an important cause of nosocomial infection and outbreaks. Although the genome of S.
Bhavya Somalapura Gangadharappa +2 more
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Resolution Ladder for High-Resolution Mass Spectrometry [PDF]
Analytical Chemistry, 2017 High-resolution mass spectrometry has become a key technology in life sciences. Since it is often unfeasible to find pairs of analytes with an appropriate mass difference to actually quantify the resolution experimentally, resolution is usually calculated from the shape of a single mass peak.
Matthias Schittmayer +1 more
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Acyl-Lipid Δ6-Desaturase May Act as a First FAD in Cyanobacteria
Biomolecules, 2022 Fatty acid desaturases (FADs) play important roles in various metabolic and adaptive pathways in all living organisms. They represent a superfamily of oxygenases that introduce double bonds into the acyl chains of fatty acids (FAs).
Alexander Y. Starikov +3 more
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Historical exposomics and high resolution mass spectrometry [PDF]
Exposome, 2021 AbstractAwareness of the exposome and its influence on health has increased in the last decade. As past exposures can cause changes in human health many years later, delving into the past is relevant for both diagnostic and prevention purposes, but remains a challenging task.
Dagny Aurich +2 more
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Advances in Ultra-High-Resolution Mass Spectrometry for Pharmaceutical Analysis
Molecules, 2023 Pharmaceutical analysis refers to an area of analytical chemistry that deals with active compounds either by themselves (drug substance) or when formulated with excipients (drug product).
Estelle Deschamps +5 more
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Fast and Accurate Identification of Candida auris by High Resolution Mass Spectrometry
Journal of Fungi, 2023 The emerging pathogen Candida auris has been associated with nosocomial outbreaks on six continents. Genetic analysis indicates simultaneous and independent emergence of separate clades of the species in different geographical locations.
Azadeh Jamalian +5 more
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Proteomic Analysis of Cardiac Adaptation to Exercise by High Resolution Mass Spectrometry
Frontiers in Molecular Biosciences, 2021 Regular exercise has many health benefits, among which is a significant reduction of cardiovascular risk. Although many beneficial effects of exercise are well described, the exact mechanisms by which exercise confers cardiovascular benefits are yet to ...
Afnan Saleh Al-Menhali +7 more
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