Results 1 to 10 of about 22,549 (161)

What is in the fish? Collaborative trial in suspect and non-target screening of organic micropollutants using LC- and GC-HRMS

Environment International, 2023
A collaborative trial involving 16 participants from nine European countries was conducted within the NORMAN network in efforts to harmonise suspect and non-target screening of environmental contaminants in whole fish samples of bream (Abramis brama ...
Sofia Lindblad, Reza Aalizadeh, Maria-Christina Nika   +2 more
exaly   +3 more sources

Automated Near Real-Time QC for LC-HRMS. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale The quality of analytical measurements is typically evaluated after completion of the entire, or possibly multiple, measurement batch(es). Automated, near real‐time quality control (QC) during LC‐HRMS acquisition can prevent reruns and sample loss by flagging issues as they ...
Mohr MJ, Strähle L, Bader T, Leurle P, Christensen JH, Seitz W, Winzenbacher R.   +6 more
europepmc   +3 more sources

Discrimination of Bipolar Disorder and Schizophrenia Patients Based on LC-HRMS Lipidomics. [PDF]

Metabolites
Background/Objectives: Schizophrenia (SCH) and bipolar disorder (BD) share overlapping symptoms and genetic factors, making differential diagnosis challenging and often leading to misdiagnosis. This study aimed to identify potential lipid biomarkers of serum capable of distinguishing BD from SCH.
Janković MR, Avramović N, Miladinović Z, Jadranin MB, Takić M, Krstić G, Gavrilović A, Miljević Č, Pantović M, Andrić Z, Radević S, Savić D, Lekić S, Tešević V, Mandić B.   +14 more
europepmc   +5 more sources

Prioritization of Unknown LC-HRMS Features Based on Predicted Toxicity Categories. [PDF]

Environ Sci Technol
Complex environmental samples contain a diverse array of known and unknown constituents. While liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS) nontargeted analysis (NTA) has emerged as an essential tool for the comprehensive study of such samples, the identification of individual constituents remains a significant ...
Turkina V, Gringhuis JT, Boot S, Petrignani A, Corthals G, Praetorius A, O'Brien JW, Samanipour S.   +7 more
europepmc   +5 more sources

Untargeted LC-HRMS Metabolomics for the Detection of Alternaria-Infected Apples Under Retail and Storage Conditions [PDF]

Toxins
Apples are highly susceptible to fungal infections, particularly by Alternaria species, which can lead to fruit deterioration and mycotoxin contamination during storage.
María Agustina Pavicich, Claudia Giménez-Campillo, José Diana Di Mavungu, Sarah De Saeger, Andrea Patriarca   +4 more
doaj   +2 more sources

Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data

Metabolites, 2020
The evaluation of liquid chromatography high-resolution mass spectrometry (LC-HRMS) raw data is a crucial step in untargeted metabolomics studies to minimize false positive findings. A variety of commercial or open source software solutions are available
Selina Hemmer, Sascha K Manier, Folker Westphal   +2 more
exaly   +3 more sources

Validation of an LC–HRMS Method for Quantifying Indoxyl Sulfate and p-Cresyl Sulfate in Human Serum [PDF]

Molecules
Accurate quantification of indoxyl sulfate (IndS) and p-cresyl sulfate (pCS) is essential for understanding their role in chronic kidney disease (CKD) progression and for developing strategies to mitigate their harmful effects, including cardiovascular ...
María Rodríguez-García, Irene Martínez, Irene Aliart, Jaime I. Sainz de Medrano, Nayra Rico, Víctor Joaquín Escudero-Saiz, Francisco Maduell, Manuel Morales-Ruiz, Gregori Casals   +8 more
doaj   +2 more sources

LC–HRMS determination of piperine on rat dried blood spots: A pharmacokinetic study

Journal of Pharmaceutical Analysis, 2016
A liquid chromatography–high resolution mass spectrometry (LC–HRMS) method was developed and validated for the determination of piperine (PPR) on dried blood spots (DBS).
Bokka Ramesh, P. Rajesh Rao Vadaparthi, Genji Sukumar, Nemali Manjula, Katragadda Suresh Babu, Potturi Sita Devi   +5 more
doaj   +3 more sources

Naive Bayes classification model for isotopologuedetection in LC-HRMS data [PDF]

Chemometrics and Intelligent Laboratory Systems, 2021
Isotopologue identification or removal is a necessary step to reduce the number of features that need to be identified in samples analyzed with non-targeted analysis. Currently available approaches rely on either predicted isotopic patterns or an arbitrary mass tolerance, requiring information on the molecular formula or instrumental error ...
Denice van Herwerden, Jake W. O'Brien, Phil M. Choi, Kevin V. Thomas, Peter J. Schoenmakers, Saer Samanipour   +5 more
openaire   +6 more sources

Measurement of Plasma Glucagon Levels Using Mass Spectrometry in Patients with Type 2 Diabetes on Maintenance Hemodialysis

Kidney & Blood Pressure Research, 2021
Background: Recently, attention has been focused on the effect of glucagon on blood glucose variability. The dynamics of glucagon have attracted attention as a new target in the treatment of diabetes patients.
Yuta Yoshizawa, Michihiro Hosojima, Hideyuki Kabasawa, Naohito Tanabe, Atsushi Miyachi, Hitoshi Hamajima, Eri Mieno, Masaki Kobayashi, Tadahiro Kitamura, Ichiei Narita, Akihiko Saito   +10 more
doaj   +1 more source