Results 1 to 10 of about 34,427 (119)
Metabolites, 2023 Untargeted and targeted approaches are the traditional metabolomics workflows acquired for a wider understanding of the metabolome under focus. Both approaches have their strengths and weaknesses.
Bashar Amer
exaly +3 more sources
Molecules, 2022 The authors of this paper conducted a comparative metabolomic analysis of Ophiocordyceps sinensis (OS), providing the metabolic profiles of the stroma (OSBSz) and sclerotia (OSBSh) of OS by widely targeted metabolomics and untargeted metabolomics.
Jinna Zhou +6 more
doaj +1 more source
Nature Communications, 2022 Unknown metabolite annotation is a grand challenge in untargeted metabolomics. Here, the authors develop knowledge-guided multi-layer networking (KGMN) to enable global metabolite annotation from knowns to unknowns in untargeted metabolomics.
Zhiwei Zhou +5 more
doaj +1 more source
Investigation of pathogenesis of hyperuricemia based on untargeted and targeted metabolomics
Scientific Reports, 2022 Hyperuricemia (HUA) seriously harms human health but the exact etiology and pathogenesis of HUA are not fully understood. Therefore, it is still of great significance to find effective biomarkers and explore the pathogenesis of HUA. Metabolomics reflects
Nankun Qin +8 more
doaj +1 more source
Nature Communications, 2023 Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an ...
Tara J. Bowen +8 more
doaj +1 more source
Frontiers in Endocrinology, 2022 PurposeTo identify the biomarkers in the critical period of development in diabetic retinopathy (DR) in Chinese with type 2 diabetes using targeted and untargeted metabolomics, and to explore the feasibility of their clinical applicationMethodsThis case ...
Zongyi Wang +12 more
doaj +1 more source
Metabolomics profiling reveals differences in proliferation between tumorigenic and non-tumorigenic Madin-Darby canine kidney (MDCK) cells [PDF]
PeerJ, 2023 Background Madin-Darby canine kidney (MDCK) cells are a cellular matrix in the production of influenza vaccines. The proliferation rate of MDCK cells is one of the critical factors that determine the vaccine production cycle.
Na Sun +11 more
doaj +2 more sources
Cell Reports Medicine, 2021 Summary: Untargeted metabolomics is used to refine the development of biomarkers for the diagnosis of cardiovascular disease. Myocardial infarction (MI) has major individual and societal consequences for patients, who remain at high risk of secondary ...
Karla N. Samman +13 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2023 Background: Early diagnosis of inherited metabolic diseases (IMDs) is important because treatment may lead to reduced mortality and improved prognosis. Due to their diversity, it is a challenge to diagnose IMDs in time, effecting an emerging need for a ...
Anke P. Willems +11 more
doaj +1 more source
Metabolites, 2021 Selection for more feed efficient dairy cows is key to improving sustainability and profitability of dairy production; however, underlying mechanisms contributing to individual animal feed efficiency are not fully understood.
Malia J. Martin +6 more
doaj +1 more source