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Extra virgin olive oil (EVOO) is one of the main ingredients of the Mediterranean diet. It is claimed as a functional food for its unique content of health-promoting compounds.
Veronica Termopoli +4 more
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One of modern analytical chemistry main challenges is providing as fast as possible results in different application fields. In this view, real-time analysis techniques are experiencing ever-increasing success as they can provide data quickly, almost ...
Adriana Arigò +6 more
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LC/MS and LC/MS/MS determination of protein tryptic digests [PDF]
Tryptic digests were analyzed by means of online microbore liquid chromatography combined with mass spectrometry (LC/MS) for some common proteins. Following conventional enzymatic digestion with trypsin, the freeze-dried residues were dissolved in high-performance liquid chromatography (HPLC) eluent and subjected to gradient reversed-phase microbore ...
Huang, Eric C., Henion, Jack D.
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Adeno-associated virus (AAV) has emerged as a leading platform for gene therapy. With the skyrocketing rate of AAV research and the prevalence of many new engineered capsids being investigated in preclinical and clinical trials, capsid characterization ...
Anh K. Lam +7 more
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Comprehensive Peak Characterization (CPC) in Untargeted LC–MS Analysis
LC–MS-based untargeted metabolomics is heavily dependent on algorithms for automated peak detection and data preprocessing due to the complexity and size of the raw data generated. These algorithms are generally designed to be as inclusive as possible in
Kristian Pirttilä +5 more
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“Notame”: Workflow for Non-Targeted LC–MS Metabolic Profiling
Metabolomics analysis generates vast arrays of data, necessitating comprehensive workflows involving expertise in analytics, biochemistry and bioinformatics in order to provide coherent and high-quality data that enable discovery of robust and ...
Anton Klåvus +15 more
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Pigments’ analysis of Citrus juicing making by‐products by LC‐MS/MS and LC‐DAD
Citrus fruits Cold Press Essential Oils (CPEOs) constitute a low-cost by-product produced during the juice making process that are composed by a volatile and a non-volatile fraction. Their non-volatile fractions are rich in valuable secondary metabolites,
Eleni D. Myrtsi +3 more
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Integrated LC-MS/MS system for plant metabolomics
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is highly sensitive, selective, and enables extensive detection of metabolites within a sample.
Yuji Sawada, Masami Yokota Hirai
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Human age-declined saliva metabolic markers determined by LC–MS
Metabolites in human biofluids reflect individual physiological states influenced by various factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non-targeted, non-invasive metabolomics using saliva of 27 healthy volunteers in ...
Takayuki Teruya +2 more
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Recent Progress in FD-LC-MS/MS Proteomics Method
Through the course of our bio-analytical chemistry studies, we developed a novel proteomics analysis method, FD-LC-MS/MS (fluorogenic derivatization-liquid chromatography-tandem mass spectrometry). This method consists of fluorogenic derivatization (FD),
Hiroshi Kobayashi +2 more
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