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Tyrosol and Hydroxytyrosol Determination in Extra Virgin Olive Oil with Direct Liquid Electron Ionization-Tandem Mass Spectrometry

open access: yesSeparations, 2021
Extra virgin olive oil (EVOO) is one of the main ingredients of the Mediterranean diet. It is claimed as a functional food for its unique content of health-promoting compounds.
Veronica Termopoli   +4 more
doaj   +1 more source

Extractive-liquid sampling electron ionization-mass spectrometry (E-LEI-MS): a new powerful combination for direct analysis

open access: yesScientific Reports, 2023
One of modern analytical chemistry main challenges is providing as fast as possible results in different application fields. In this view, real-time analysis techniques are experiencing ever-increasing success as they can provide data quickly, almost ...
Adriana Arigò   +6 more
doaj   +1 more source

LC/MS and LC/MS/MS determination of protein tryptic digests [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 1990
Tryptic digests were analyzed by means of online microbore liquid chromatography combined with mass spectrometry (LC/MS) for some common proteins. Following conventional enzymatic digestion with trypsin, the freeze-dried residues were dissolved in high-performance liquid chromatography (HPLC) eluent and subjected to gradient reversed-phase microbore ...
Huang, Eric C., Henion, Jack D.
openaire   +2 more sources

Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS

open access: yesMolecular Therapy: Methods & Clinical Development, 2022
Adeno-associated virus (AAV) has emerged as a leading platform for gene therapy. With the skyrocketing rate of AAV research and the prevalence of many new engineered capsids being investigated in preclinical and clinical trials, capsid characterization ...
Anh K. Lam   +7 more
doaj   +1 more source

Comprehensive Peak Characterization (CPC) in Untargeted LC–MS Analysis

open access: yesMetabolites, 2022
LC–MS-based untargeted metabolomics is heavily dependent on algorithms for automated peak detection and data preprocessing due to the complexity and size of the raw data generated. These algorithms are generally designed to be as inclusive as possible in
Kristian Pirttilä   +5 more
doaj   +1 more source

“Notame”: Workflow for Non-Targeted LC–MS Metabolic Profiling

open access: yesMetabolites, 2020
Metabolomics analysis generates vast arrays of data, necessitating comprehensive workflows involving expertise in analytics, biochemistry and bioinformatics in order to provide coherent and high-quality data that enable discovery of robust and ...
Anton Klåvus   +15 more
doaj   +1 more source

Pigments’ analysis of Citrus juicing making by‐products by LC‐MS/MS and LC‐DAD

open access: yesMethodsX, 2022
Citrus fruits Cold Press Essential Oils (CPEOs) constitute a low-cost by-product produced during the juice making process that are composed by a volatile and a non-volatile fraction. Their non-volatile fractions are rich in valuable secondary metabolites,
Eleni D. Myrtsi   +3 more
doaj   +1 more source

Integrated LC-MS/MS system for plant metabolomics

open access: yesComputational and Structural Biotechnology Journal, 2013
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is highly sensitive, selective, and enables extensive detection of metabolites within a sample.
Yuji Sawada, Masami Yokota Hirai
doaj   +3 more sources

Human age-declined saliva metabolic markers determined by LC–MS

open access: yesScientific Reports, 2021
Metabolites in human biofluids reflect individual physiological states influenced by various factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non-targeted, non-invasive metabolomics using saliva of 27 healthy volunteers in ...
Takayuki Teruya   +2 more
doaj   +1 more source

Recent Progress in FD-LC-MS/MS Proteomics Method

open access: yesFrontiers in Chemistry, 2021
Through the course of our bio-analytical chemistry studies, we developed a novel proteomics analysis method, FD-LC-MS/MS (fluorogenic derivatization-liquid chromatography-tandem mass spectrometry). This method consists of fluorogenic derivatization (FD),
Hiroshi Kobayashi   +2 more
doaj   +1 more source

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