Results 31 to 40 of about 124,046 (257)

METABOLÔMICA: DEFINIÇÕES, ESTADO-DA-ARTE E APLICAÇÕES REPRESENTATIVAS

Química Nova
Metabolomics is an emerging and promising omics approach used to understand biological mechanisms. By untargeted and targeted metabolomics analyses, metabolites are determined in biological samples (fluids, cells, tissues, etc.) by comparison of control ...
Gisele A. B. Canuto, José Luiz da Costa, Pedro L. R. da Cruz, Ana Rosa L. de Souza, Andréa T. Faccio, Aline Klassen, Karina T. Rodrigues, Marina F. M. Tavares   +7 more
doaj   +1 more source

A Python-Based Pipeline for Preprocessing LC–MS Data for Untargeted Metabolomics Workflows

Metabolites, 2020
Preprocessing data in a reproducible and robust way is one of the current challenges in untargeted metabolomics workflows. Data curation in liquid chromatography–mass spectrometry (LC–MS) involves the removal of biologically non-relevant features ...
Gabriel Riquelme, Nicolás Zabalegui, Pablo Marchi, Christina M. Jones, María Eugenia Monge   +4 more
doaj   +1 more source

Symposium 2: Modern approaches to nutritional research challenges: Targeted and non-targeted approaches for metabolite profiling in nutritional research. [PDF]

, 2010
The present report discusses targeted and non-targeted approaches to monitor single nutrients and global metabolite profiles in nutritional research. Non- targeted approaches such as metabolomics allow for the global description of metabolites in a ...
Lodge, John K., Lodge, John
core   +1 more source

Characterization of Cabernet Sauvignon Wines by Untargeted HS-SPME GC-QTOF-MS

Molecules, 2022
Untargeted metabolomics approaches are emerging as powerful tools for the quality evaluation and authenticity of food and beverages and have been applied to wine science.
Alejandra Chávez-Márquez, Alfonso A. Gardea, Humberto González-Rios, Luz Vazquez-Moreno   +3 more
doaj   +1 more source

Metabolomics and wood development [PDF]

, 2013
The tree industry is one of Sweden's most important economic sectors, producing pulp, paper, wooden goods and wood as a bioenergy source. Understanding the biology behind the processes of tree growth and wood development is a key to maximizing the use of
Johansson, Annika I.
core   +1 more source

Untargeted Metabolomic Analysis Combined With Multivariate Statistics Reveal Distinct Metabolic Changes in GPR40 Agonist-Treated Animals Related to Bile Acid Metabolism

Frontiers in Molecular Biosciences, 2021
Metabolomics has been increasingly applied to biomarker discovery, as untargeted metabolic profiling represents a powerful exploratory tool for identifying causal links between biomarkers and disease phenotypes.
Hannes Doerfler, Dana-Adriana Botesteanu, Stefan Blech, Ralf Laux   +3 more
doaj   +1 more source

Metabolomics and human nutrition [PDF]

, 2011
The present report summarises a workshop convened by the UK Food Standards Agency (Agency) on 25 March 2010 to discuss the current Agency's funded research on the use of metabolomics technologies in human nutrition research.
Mathers, John, Sandy Primrose, Kirkpatrick, Verity, Chris Seal, Primrose, Sandy, Beckmann, Manfred, Draper, John, John H. Beattie, Elsom, Rachel, John Draper, Sumanto Haldar, Seal, Chris, Augustin Scalbert, Beattie, John, Jenab, Mazda, Keun, Hector, Hector Keun, Rachel Elsom, Haldar, Sumanto, John K. Lodge, Manfred Beckmann, Scalbert, Augustin, Lodge, John, Verity Kirkpatrick, John C. Mathers, Mazda Jenab   +25 more
core   +1 more source

A Taguchi Design of Experiments Approach for Untargeted Metabolomics Sample Preparation Optimization [PDF]

, 2022
Metabolomics commonly uses analytical techniques such as nuclear magnetic resonance (NMR) and liquid chromatography coupled to mass spectrometry (LC-MS) to quantify and identify metabolites associated with biological variation.
Arthur S., Edison, I. Jonathan, Amster, Brianna M., Garcia, Goncalo J., Gouveia, Ricardo M., Borges, Franklin E., Leach III, Amanda O., Shaver   +6 more
core   +2 more sources

The Combination of Untargeted Metabolomics and Machine Learning Predicts the Biosynthesis of Phenolic Compounds in Bryophyllum Medicinal Plants (Genus Kalanchoe)

Plants, 2021
Phenolic compounds constitute an important family of natural bioactive compounds responsible for the medicinal properties attributed to Bryophyllum plants (genus Kalanchoe, Crassulaceae), but their production by these medicinal plants has not been ...
Pascual García-Pérez, Leilei Zhang, Begoña Miras-Moreno, Eva Lozano-Milo, Mariana Landin, Luigi Lucini, Pedro P. Gallego   +6 more
doaj   +1 more source

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu   +10 more
wiley   +1 more source