Results 1 to 10 of about 81,893 (99)
Untargeted-targeted metabolomics: energy metabolism characteristics in heart failure staging and discovery of novel biomarkers [PDF]
Journal of Translational MedicineBackground Heart Failure represents the severe stage of various heart diseases. Its global morbidity and mortality are on the rise, making it a serious public health issue that imposes a heavy burden on patients’ families and society.
Xiao Zhang +4 more
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Research Progress and Trends in Metabolomics of Fruit Trees
Frontiers in Plant Science, 2022 Metabolomics is an indispensable part of modern systems biotechnology, applied in the diseases’ diagnosis, pharmacological mechanism, and quality monitoring of crops, vegetables, fruits, etc.
Jing Li +30 more
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Molecules, 2022 The authors of this paper conducted a comparative metabolomic analysis of Ophiocordyceps sinensis (OS), providing the metabolic profiles of the stroma (OSBSz) and sclerotia (OSBSh) of OS by widely targeted metabolomics and untargeted metabolomics.
Jinna Zhou +6 more
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Investigation of pathogenesis of hyperuricemia based on untargeted and targeted metabolomics
Scientific Reports, 2022 Hyperuricemia (HUA) seriously harms human health but the exact etiology and pathogenesis of HUA are not fully understood. Therefore, it is still of great significance to find effective biomarkers and explore the pathogenesis of HUA. Metabolomics reflects
Nankun Qin +8 more
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Frontiers in Immunology, 2022 The FcR for IgM (FcµR) is the newest member of the FcR family, selectively expressed by lymphocytes, and distinct from FcRs for switched Ig isotypes that are expressed by various immune cell types and non-hematopoietic cells. From studies of Fcmr-ablated
Pedram Mahmoudi Aliabadi +9 more
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Development, characterization and comparisons of targeted and non-targeted metabolomics methods. [PDF]
PLoS ONE, 2018 The potential of a metabolomics method to detect statistically significant perturbations in the metabolome of an organism is enhanced by excellent analytical precision, unequivocal identification, and broad metabolomic coverage.
Anton Ribbenstedt +2 more
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Optimising a urinary extraction method for non-targeted GC–MS metabolomics
Scientific Reports, 2023 Urine is ideal for non-targeted metabolomics, providing valuable insights into normal and pathological cellular processes. Optimal extraction is critical since non-targeted metabolomics aims to analyse various compound classes.
Cara Olivier, Bianca Allen, Laneke Luies
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GSimp: A Gibbs sampler based left-censored missing value imputation approach for metabolomics studies. [PDF]
PLoS Computational Biology, 2018 Left-censored missing values commonly exist in targeted metabolomics datasets and can be considered as missing not at random (MNAR). Improper data processing procedures for missing values will cause adverse impacts on subsequent statistical analyses ...
Runmin Wei +5 more
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Targeted metabolomics analysis of postoperative delirium
Scientific Reports, 2021 Postoperative delirium is the most common complication among older adults undergoing major surgery. The pathophysiology of delirium is poorly understood, and no blood-based, predictive markers are available.
Bridget A. Tripp +12 more
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Metabolites, 2015 Tandem mass spectrometry (MS/MS) with Sequential Window Acquisition of all Theoretical (SWATH) mass spectra generates a comprehensive archive of lipid species within an extract for retrospective, quantitative MS/MS analysis.
Jeevan K. Prasain +4 more
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