Results 31 to 40 of about 90,676 (185)

Metabolomic comparison followed by cross-validation of enzyme-linked immunosorbent assay to reveal potential biomarkers of diabetic retinopathy in Chinese with type 2 diabetes

Frontiers in Endocrinology, 2022
PurposeTo identify the biomarkers in the critical period of development in diabetic retinopathy (DR) in Chinese with type 2 diabetes using targeted and untargeted metabolomics, and to explore the feasibility of their clinical applicationMethodsThis case ...
Zongyi Wang, Jiyang Tang, Enzhong Jin, Chi Ren, Siying Li, Linqi Zhang, Yusheng Zhong, Yu Cao, Jianmin Wang, Wei Zhou, Mingwei Zhao, Lvzhen Huang, Jinfeng Qu   +12 more
doaj   +1 more source

A Targeted Serum Metabolomics GC-MS Approach Identifies Predictive Blood Biomarkers for Retained Placenta in Holstein Dairy Cows [PDF]

, 2021
The retained placenta is a common pathology of dairy cows. It is associated with a significant drop in the dry matter intake, milk yield, and increased susceptibility of dairy cows to metritis, mastitis, and displaced abomasum.
Guanshi Zhang, Burim N. Ametaj, Grzegorz Zwierzchowski, David S. Wishart, Dawid Tobolski, Rupasri Mandal   +5 more
core   +1 more source

Body fat free mass is associated with the serum metabolite profile in a population-based study. [PDF]

, 2012
To characterise the influence of the fat free mass on the metabolite profile in serum samples from participants of the population-based KORA (Cooperative Health Research in the Region of Augsburg) S4 study.
Döring, Angela, Wichmann, Heinz-Erich, Fabian J. Theis, Elisabeth Altmaier, Karsten Suhre (67967), Gieger, C., Christian Gieger, Christa Meisinger (39940), Döring, A., Krumsiek, J., Karsten Suhre, Gabi Kastenmüller (127487), Prehn, C., Linseisen Jakob, Römisch-Margl, Werner, Jan Krumsiek (127460), Jourdan, Carolin, Christian Gieger (87555), Theis, F.J., Wang-Sattler, R., Jan Krumsiek, Kastenmüller, Gabi, H.-Erich Wichmann (72009), Gieger Christian, Altmaier, E., Wichmann, H.-E., Angela Döring (64291), Illig, T., Fabian J Theis, Linseisen, J., Peters, Annette, Illig Thomas, Kastenmüller Gabi, Theis, Fabian J., Jakob Linseisen, Peters Annette, Altmaier, Elisabeth, Wichmann H.-Erich, Annette Peters (62601), Rui Wang-Sattler (36841), Carolin Jourdan (155791), Jerzy Adamski, Linseisen, Jakob, Römisch-Margl Werner, Angela Döring, Annette Peters, Wang-Sattler, Rui, Krumsiek, Jan, Theis Fabian J., Thomas Illig (44906), Petersen Ann-Kristin, Werner Römisch-Margl, Ann-Kristin Petersen (149959), Jakob Linseisen (123573), Werner Römisch-Margl (127480), Peters, A., Krumsiek Jan, Elisabeth Altmaier (155799), Illig, Thomas, Wang-Sattler Rui, Adamski, Jerzy, Thomas Illig, Cornelia Prehn, H-Erich Wichmann, Meisinger Christa, Christa Meisinger, Jourdan, C., Römisch-Margl, W., Jerzy Adamski (127482), Petersen, Ann-Kristin, Gabi Kastenmüller, Suhre Karsten, Fabian J. Theis (127485), Gieger, Christian, Suhre, K., Meisinger, C., Cornelia Prehn (137977), Ann-Kristin Petersen, Adamski Jerzy, Kastenmüller, G., Prehn, Cornelia, Jourdan Carolin, Rui Wang-Sattler, Petersen, A.-K., Rui Wang, Meisinger, Christa, Döring Angela, Prehn Cornelia, Adamski, J., Suhre, Karsten, Altmaier Elisabeth, Carolin Jourdan   +91 more
core   +1 more source

Application of Metabolomics in Pediatric Asthma: Prediction, Diagnosis and Personalized Treatment [PDF]

, 2021
Asthma in children remains a significant public health challenge affecting 5–20% of children in Europe and is associated with increased morbidity and societal healthcare costs.
Dimitris Tsoukalas, Anastasia Varvarigou, Maria Michelle Papamichael, Eirini-Sofia Frima, Spyridoula Georgaki, Charis Katsardis, Evangelia Sarandi   +6 more
core   +1 more source

A metabolomic investigation of the effects of vitamin E supplementation in humans [PDF]

, 2012
Background Vitamin E is a nutrient with both antioxidant and non-antioxidant activities and has been shown to modulate the function of a number of cell types in vitro and in human studies.
John K Lodge, Max Wong, Lodge John K, Lodge, John, Wong, Max, Wong Max   +5 more
core   +2 more sources

Secondary Metabolic Pathway-Targeted Metabolomics [PDF]

, 2016
This chapter provides step-by-step methods for building secondary metabolic pathway-targeted molecular networks to assess microbial natural product biosynthesis at a systems level and to aid in downstream natural product discovery efforts. Methods described include high-resolution mass spectrometry (HRMS)-based comparative metabolomics, pathway ...
Maria I, Vizcaino, Jason M, Crawford
openaire   +2 more sources

Non-targeted metabolomics aids in sex pheromone identification: a proof-of-concept study with the triangulate cobweb spider, Steatoda triangulosa

Scientific Reports, 2023
Targeted metabolomics has been widely used in pheromone research but may miss pheromone components in study organisms that produce pheromones in trace amount and/or lack bio-detectors (e.g., antennae) to readily locate them in complex samples.
Andreas Fischer, Andrea C. Roman-Torres, Jane Vurdela, Yerin Lee, Nastaran Bahar, Regine Gries, Santosh Alamsetti, Hongwen Chen, Gerhard Gries   +8 more
doaj   +1 more source

Metabolomics of infectious diseases in the era of personalized medicine

Frontiers in Molecular Biosciences, 2023
Infectious diseases continue to be a major cause of morbidity and mortality worldwide. Diseases cause perturbation of the host’s immune system provoking a response that involves genes, proteins and metabolites.
Mahbuba Rahman, Herb E. Schellhorn
doaj   +1 more source

Exometabolomics Approaches in Studying the Application of Lignocellulosic Biomass as Fermentation Feedstock

Metabolites, 2013
Lignocellulosic biomass is the future feedstock for the production of biofuel and bio-based chemicals. The pretreatment-hydrolysis product of biomass, so-called hydrolysate, contains not only fermentable sugars, but also compounds that inhibit its ...
Peter J. Punt, Ying Zha
doaj   +1 more source

Targeted Metabolomics Sample Preparation

, 2022
Protocol for intracellular metabolite extraction from different cell lines for targeted metabolomics measurement using a 6-well or 24-well plate format.
Wiedmer, Tabea, Jarret, Abigail, Lindinger, Sabrina   +2 more
openaire   +1 more source