Results 51 to 60 of about 90,676 (185)

Bacterial Metabolomics: Sample Preparation Methods

Biochemistry Research International, 2022
Metabolomics is a comprehensive analysis of metabolites existing in biological systems. As one of the important “omics” tools, the approach has been widely employed in various fields in helping to better understand the complex cellular metabolic states ...
Khairunnisa Mohd Kamal, Mohd Hafidz Mahamad Maifiah, Nusaibah Abdul Rahim, Yumi Zuhanis Has-Yun Hashim, Muhamad Shirwan Abdullah Sani, Kamalrul Azlan Azizan   +5 more
doaj   +1 more source

Untargeted Metabolomic Analysis Hits the Target [PDF]

Clinical Chemistry, 2007
Propionic (PA) and methylmalonic (MMA) acidemias are inborn errors of the metabolism of several important amino acids, the side chain of the cholesterol molecule, and dietary odd chain-length fatty acids. PA results from a deficiency of mitochondrial propionyl-CoA carboxylase, an enzyme that requires biotin as a cofactor and converts propionyl-CoA to D-
openaire   +2 more sources

Non-targeted metabolomics in sport and exercise science [PDF]

Journal of Sports Sciences, 2017
Metabolomics incorporates the study of metabolites that are produced and released through physiological processes at both the systemic and cellular levels. Biological compounds at the metabolite level are of paramount interest in the sport and exercise sciences, although research in this field has rarely been referred to with the global 'omics ...
Liam M. Heaney, Kevin Deighton, Toru Suzuki   +2 more
openaire   +3 more sources

Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics [PDF]

, 2019
Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable incidences. IEMs are caused by disrupting enzyme activities in specific metabolic pathways by genetic mutations, either directly or indirectly by cofactor deficiencies ...
Ismail, Israa T, Showalter, Megan R, Oliver Fiehn, Fiehn, Oliver, Israa T Ismail, Megan R Showalter   +5 more
core   +1 more source

Pleiotropic effects of 4-hydroxynonenal on oxidative burst and phagocytosis in neutrophils

Redox Biology, 2016
Metabolic control of cellular function is significant in the context of inflammation-induced metabolic dysregulation in immune cells. Generation of reactive oxygen species (ROS) such as hydrogen peroxide and superoxide are one of the critical events that
Balu K. Chacko, Stephanie B. Wall, Philip A. Kramer, Saranya Ravi, Tanecia Mitchell, Michelle S. Johnson, Landon Wilson, Stephen Barnes, Aimee Landar, Victor M. Darley-Usmar   +9 more
doaj   +1 more source

METABOLÔMICA: DEFINIÇÕES, ESTADO-DA-ARTE E APLICAÇÕES REPRESENTATIVAS

Química Nova
Metabolomics is an emerging and promising omics approach used to understand biological mechanisms. By untargeted and targeted metabolomics analyses, metabolites are determined in biological samples (fluids, cells, tissues, etc.) by comparison of control ...
Gisele A. B. Canuto, José Luiz da Costa, Pedro L. R. da Cruz, Ana Rosa L. de Souza, Andréa T. Faccio, Aline Klassen, Karina T. Rodrigues, Marina F. M. Tavares   +7 more
doaj   +1 more source

A Data Mining Metabolomics Exploration of Glaucoma [PDF]

, 2020
Glaucoma is an age related disease characterized by the progressive loss of retinal ganglion cells, which are the neurons that transduce the visual information from the retina to the brain. It is the leading cause of irreversible blindness worldwide.
Gohier, Philippe, Guehlouz, Khadidja, Leruez, Stéphanie, Jeanne Muller, Vincent Procaccio, Bocca, Cinzia, Guy Lenaers, Milea, Dan, Philippe Gohier, Procaccio, Vincent, Lenaers, Guy, Gilles Simard, Pascal Reynier, Chao de La Barca, Juan, Manuel, Muller, Jeanne, Simard, Gilles, Stéphanie Leruez, Judith Kouassi Nzoughet, Kouassi Nzoughet, Judith, Dan Milea, Odile Blanchet, Blanchet, Odile, Dominique Bonneau, Bonneau, Dominique, Khadidja Guehlouz, Reynier, Pascal, Cinzia Bocca, Juan M. Chao de la Barca   +27 more
core   +1 more source

Untargeted and Targeted Metabolomic Profiling of Australian Indigenous Fruits [PDF]

Metabolites, 2020
Selected Australian native fruits such as Davidson’s plum, finger lime and native pepperberry have been reported to demonstrate potent antioxidant activity. However, comprehensive metabolite profiling of these fruits is limited, therefore the compounds responsible are unknown, and further, the compounds of nutritional value in these native fruits are ...
Vuanghao Lim, Sara Ghorbani Gorji, Venea Dara Daygon, Melissa Fitzgerald   +3 more
openaire   +6 more sources

Triple acquisition mass spectrometry (TRAM) combining targeted and non-targeted metabolomics in a single run [PDF]

We introduce TRAM, a triple acquisition strategy on high-speed, time-of-flight mass spectrometry for merging non-targeted and targeted metabolomics into one run.
Marvin, Glas, Bruno, Stelzer, Daniela, Loetsch, Lisa, Panzenboeck, Christian, Dorfer, Dorian, Hirschmann, Harald, Schoeny, Elisabeth, Foels, Gunda, Koellensperger, Marlene, Pühringer, Evelyn, Rampler   +10 more
core   +1 more source

Non-mass spectrometric targeted single-cell metabolomics [PDF]

, 2023
Metabolic assays serve as pivotal tools in biomedical research, offering keen insights into cellular physiological and pathological states. While mass spectrometry (MS)-based metabolomics remains the gold standard for comprehensive, multiplexed analyses ...
Zhili Guo, Xue, Min, Wei, Wei, Heath, James R, Zhonghan Li, Min Xue, Cheng, Hanjun, Hanjun Cheng, Tang, Yin, Wei Wei, Guo, Zhili, James R. Heath, Li, Zhonghan, Yin Tang   +13 more
core   +1 more source