Results 51 to 60 of about 7,670,364 (343)

Inter-laboratory reproducibility of fast gas chromatography-electron impact-time of flight mass spectrometry (GC-EI-TOF/MS) based plant metabolomics [PDF]

, 2009
The application of gas chromatography¿mass spectrometry (GC¿MS) to the `global¿ analysis of metabolites in complex samples (i.e. metabolomics) has now become routine.
Dunn, Warwick, Luedemann, A., Lüdemann, A., Arjen Lommen, Goodacre, R., Lommen, Arjen, Lorraine Kay, Dunn, Warwick B., Joachim Kopka, Allwood, J. William, de Koning, S., Erban, Alexander, Kay, Lorraine, Sjaak de Koning, Ralf Löscher, Erban, A., Alexander Erban, Royston Goodacre, de Koning, Sjaak, Löscher, R., Goodacre, Royston, Allwood, J., Kay, L., Allwood, J.W., Dun, W.B., Lommen, A., Kopka, J., Koning, S., Alexander Luedemann, Dunn, W. B., Allwood, J. W., J. William Allwood, Luedemann, Alexander, Dunn, Warwick B, Dunn, W., Kopka, Joachim, Allwood, James, Löscher, Ralf, Warwick B. Dunn   +38 more
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An assessment of AcquireX and Compound Discoverer software 3.3 for non-targeted metabolomics

Scientific Reports
We used the Exploris 240 mass spectrometer for non-targeted metabolomics on Saccharomyces cerevisiae strain BY4741 and tested AcquireX software for increasing the number of detectable compounds and Compound Discoverer 3.3 software for identifying ...
Bret Cooper, Ronghui Yang
semanticscholar   +1 more source

Pleiotropic effects of 4-hydroxynonenal on oxidative burst and phagocytosis in neutrophils

Redox Biology, 2016
Metabolic control of cellular function is significant in the context of inflammation-induced metabolic dysregulation in immune cells. Generation of reactive oxygen species (ROS) such as hydrogen peroxide and superoxide are one of the critical events that
Balu K. Chacko, Stephanie B. Wall, Philip A. Kramer, Saranya Ravi, Tanecia Mitchell, Michelle S. Johnson, Landon Wilson, Stephen Barnes, Aimee Landar, Victor M. Darley-Usmar   +9 more
doaj   +1 more source

Bacterial Metabolomics: Sample Preparation Methods

Biochemistry Research International, 2022
Metabolomics is a comprehensive analysis of metabolites existing in biological systems. As one of the important “omics” tools, the approach has been widely employed in various fields in helping to better understand the complex cellular metabolic states ...
Khairunnisa Mohd Kamal, Mohd Hafidz Mahamad Maifiah, Nusaibah Abdul Rahim, Yumi Zuhanis Has-Yun Hashim, Muhamad Shirwan Abdullah Sani, Kamalrul Azlan Azizan   +5 more
doaj   +1 more source

Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19

Scientific Reports, 2021
Research exploring the development and outcome of COVID-19 infections has led to the need to find better diagnostic and prognostic biomarkers. This cross-sectional study used targeted metabolomics to identify potential COVID-19 biomarkers that predicted ...
Yamilé López-Hernández, J. Monárrez-Espino, Ana Sofía Herrera-Van Oostdam, J. E. C. Delgado, Lun Zhang, J. Zheng, J. O. Valdez, R. Mandal, Fátima de Lourdes Ochoa González, J. Borrego, Flor María Trejo Medinilla, J. A. López, José Antonio Enciso Moreno, D. Wishart   +13 more
semanticscholar   +1 more source

Targeted metabolomics of CSF in healthy individuals and patients with secondary progressive multiple sclerosis using high-resolution mass spectrometry

, 2020
Introduction: Standardized commercial kits enable targeted metabolomics analysis and may thus provide an attractive complement to the more explorative approaches.
Khoonsari, PE, Carlsson, H, Kultima, Kim, Emami Khoonsari, Payam,, Emami Khoonsari, Payam, Åkerfeldt, Torbjörn,, Burman, J, Herman, Stephanie,, Akerfeldt, T, Svenningsson, Anders, Abujrais, S, Svenningsson, A,, Abujrais, Sandy, Herman, Stephanie, Burman, Joachim, Burman, Joachim,, Carlsson, Henrik, Abujrais, Sandy,, Carlsson, Henrik,, Svenningsson, Anders,, Kultima, K, Kultima, Kim,, Herman, S, Åkerfeldt, Torbjörn   +23 more
core   +1 more source

Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection

Gut microbes
The gut-to-lung axis is critical during respiratory infections, including influenza A virus (IAV) infection. In the present study, we used high-resolution shotgun metagenomics and targeted metabolomic analysis to characterize influenza-associated changes
S. Heumel, Vinícius de Rezende Rodovalho, Charlotte Urien, Florian Specque, Patrícia Brito Rodrigues, C. Robil, Lou Delval, V. Sencio, A. Descat, L. Deruyter, S. Ferreira, Marina Gomes Machado, Adeline Barthélémy, Fabiola Silva Angulo, Joel T. Haas, Jean François Goosens, I. Wolowczuk, C. Grangette, Yves Rouillé, G. Grimaud, M. Lenski, Benjamin Hennart, Marco Aurélio Ramirez Vinolo, François Trottein   +23 more
semanticscholar   +1 more source

Simplivariate Models: Ideas and First Examples [PDF]

, 2008
One of the new expanding areas in functional genomics is metabolomics: measuring the metabolome of an organism. Data being generated in metabolomics studies are very diverse in nature depending on the design underlying the experiment.
Werf, M.J. van der, Hendriks, M.M.W.B., Johan A. Westerhuis, Ruud Berger, Jos A Hageman, Westerhuis Johan A., Age K Smilde, Hendriks Margriet M. W. B., Smilde, A.K.; id_orcid, Mariët J. van der Werf, Johan A Westerhuis, Smilde, A.K., Berger, R., Age K. Smilde, Margriet M. W. B. Hendriks, Smilde Age K., Berger Ruud, Westerhuis, J.A., van der Werf, M.J., Jos A. Hageman, Hageman, J.A., Mariët J van der Werf, Hageman Jos A., Westerhuis, J.A.; id_orcid, Werf, M.J., van der, Margriet M W B Hendriks, van der Werf Mariët J.   +26 more
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METABOLÔMICA: DEFINIÇÕES, ESTADO-DA-ARTE E APLICAÇÕES REPRESENTATIVAS

Química Nova
Metabolomics is an emerging and promising omics approach used to understand biological mechanisms. By untargeted and targeted metabolomics analyses, metabolites are determined in biological samples (fluids, cells, tissues, etc.) by comparison of control ...
Gisele A. B. Canuto, José Luiz da Costa, Pedro L. R. da Cruz, Ana Rosa L. de Souza, Andréa T. Faccio, Aline Klassen, Karina T. Rodrigues, Marina F. M. Tavares   +7 more
doaj   +1 more source

mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data [PDF]

, 2013
<p>Motivation: Stable isotope-labelling experiments have recently gained increasing popularity in metabolomics studies, providing unique insights into the dynamics of metabolic fluxes, beyond the steady-state information gathered by routine mass ...
Achcar, Fiona,, Chokkathukalam, Achuthanunni, Creek, DJ, Barrett, M.P., Chokkathukalam, A., Breitling, Rainer, Creek, D.J., Breitling, R., Breitling, Rainer,, Achcar, Fiona, Achcar, F., Chokkathukalam, Achuthanunni,, Breitling, R, Jankevics, A, Jankevics, A., Jankevics, Andris, Creek, Darren J.,, Creek, Darren J., Achcar, F, Barrett, MP, Barrett, Michael P., Chokkathukalam, A, Jankevics, Andris,, Barrett, Michael P.,   +23 more
core   +3 more sources