Results 61 to 70 of about 90,676 (185)

SmartPeak Automates Targeted and Quantitative Metabolomics Data Processing [PDF]

Analytical Chemistry, 2020
Abstract SmartPeak is an application that encapsulates advanced algorithms to enable fast, accurate, and automated processing of CE-, GC- and LC-MS(/MS) data, and HPLC data for targeted and semi-targeted metabolomics, lipidomics, and fluxomics experiments. Highlights
Svetlana Kutuzova, Pasquale Colaianni, Hannes Röst, Timo Sachsenberg, Oliver Alka, Oliver Kohlbacher, Bo Burla, Federico Torta, Lars Schrübbers, Mette Kristensen, Lars Nielsen, Markus J. Herrgård, Douglas McCloskey   +12 more
openaire   +5 more sources

Metabolic correlations between kidney and eye in a mouse model of oxygen-induced retinopathy and retinopathy of prematurity

BMJ Open Ophthalmology
Introduction Retinopathy of prematurity (ROP) is one of the leading causes of babies’ visual impairment and blindness. There is no effective prevention and treatment of ROP so far, and the shared genetic and developmental similarities among the brain ...
Jie Sun, Guoming Zhang, Yulin Zhang, Xiaofeng Lu, Zixin Fan, Yuhang Yang, Lijun Dong, Hui Qi, Yinsheng Zhang, Xiaoyan Chai, Dongting Wu, Hetian Lei   +11 more
doaj   +1 more source

Increased Association of Deamidated αA-N101D with Lens membrane of transgenic αAN101D vs. wild type αA mice: potential effects on intracellular ionic imbalance and membrane disorganization

BMC Ophthalmology, 2020
We have generated two mouse models, in one by inserting the human lens αAN101D transgene in CRYαAN101D mice, and in the other by inserting human wild-type αA-transgene in CRYαAWT mice.
Om Srivastava, Kiran Srivastava, Roy Joseph, Landon Wilson   +3 more
doaj   +1 more source

Metabolic Characterization of the Common Marmoset (Callithrix jacchus). [PDF]

PLoS ONE, 2015
High-resolution metabolomics has created opportunity to integrate nutrition and metabolism into genetic studies to improve understanding of the diverse radiation of primate species.
Young-Mi Go, Yongliang Liang, Karan Uppal, Quinlyn A Soltow, Daniel E L Promislow, Lynn M Wachtman, Dean P Jones   +6 more
doaj   +1 more source

Rifampicin-Mediated Metabolic Changes in Mycobacterium tuberculosis

Metabolites, 2022
Mycobacterium tuberculosis (Mtb) is considered to be a devastating pathogen worldwide, affecting millions of people globally. Several drugs targeting distinct pathways are utilized for the treatment of tuberculosis.
Soujanya D. Yelamanchi, Archita Mishra, Santosh Kumar Behra, Gayathree Karthikkeyan, Thottethodi Subrahmanya Keshava Prasad, Avadhesha Surolia   +5 more
doaj   +1 more source

Application of Metabolomics in Obesity-Related Childhood Asthma Subtyping: A Narrative Scoping Review [PDF]

, 2023
Obesity-related asthma is a heterogeneous childhood asthma phenotype with rising prevalence. Observational studies identify early-life obesity or weight gain as risk factors for childhood asthma development.
Andrew Bush, Zhaozhong Zhu, Valentina Fainardi, Sejal Saglani, Carlos A. Camargo, Heidi Makrinioti, Kohei Hasegawa   +6 more
core   +1 more source

Targeted Plasma Metabolic Profiles and Risk of Recurrence in Stage II and III Colorectal Cancer Patients: Results from an International Cohort Consortium

Metabolites, 2021
The identification of patients at high-risk for colorectal cancer (CRC) recurrence remains an unmet clinical need. The aim of this study was to investigate associations of metabolites with risk of recurrence in stage II/III CRC patients.
Jennifer Ose, Biljana Gigic, Stefanie Brezina, Tengda Lin, Andreas Baierl, Anne J. M. R. Geijsen, Eline van Roekel, Nivonirina Robinot, Audrey Gicquiau, David Achaintre, Pekka Keski-Rahkonen, Fränzel J. B. van Duijnhoven, Tanja Gumpenberger, Andreana N. Holowatyj, Dieuwertje E. Kok, Annaleen Koole, Petra Schrotz-King, Alexis B. Ulrich, Martin Schneider, Arve Ulvik, Per-Magne Ueland, Matty P. Weijenberg, Nina Habermann, Augustin Scalbert, Andrea Gsur, Cornelia M. Ulrich   +25 more
doaj   +1 more source

Bile Acid Aspiration Associates with CLAD and Affects the Bronchial District Lipid Profile: Targeted Bile Acid Metabolomics and Lipidomics in Bronchial Washing. [PDF]

, 2016
Bile Acid Aspiration Associates with CLAD and Affects the Bronchial District Lipid Profile: Targeted Bile Acid Metabolomics and Lipidomics in Bronchial ...
Kim C, G. Di Paolo, Briganti D, H. Robbins1, F. Meloni, Sreekanth S, S. Arcasoy, Aramini B, Zhou B, L. Shah, J. Sonett, F. D'Ovidio., Raza K, Chan R   +13 more
core   +1 more source

Metabolomics datasets [PDF]

, 2023
Metabolomics datasets as follows: Metabolomics MDA CAF-CDM vs plastic: Non-targeted metabolomics analysis of metabolistes extracted from breast cancer cells (MDA-MB-231), grown on plastic or cancer associate fibroblasts (CAF)-generated cell derived ...
Elena Rainero (2750389)
core   +1 more source

Targeted Blood Metabolomic Study on Retinopathy of Prematurity

Investigative Opthalmology & Visual Science, 2020
This study aims at exploring alterations of major metabolites and metabolic pathways in retinopathy of prematurity (ROP) infants and identifying biomarkers that may merit early diagnosis of ROP.We analyzed targeted metabolites from 81 premature infants (
Yang, Yuhang, Wu, Zhenquan, Li, Sitao, Yang, Mingmin, Xiao, Xin, Lian, Chaohui, Wen, Wei, He, Honghui, Zeng, Jian, Wang, Jiantao, Zhang, Guoming   +10 more
openaire   +2 more sources